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  1. No Access

    Article

    Juniperus chinensis and the functional compounds, cedrol and widdrol, ameliorate α-melanocyte stimulating hormone-induced melanin formation in B16F10 cells

    Anti-melanogenic activities of Juniperus chinensis methanol extracts (JCM) and isolation of functional compounds were investigated. JCM possessed potent anti-oxidative and tyrosinase inhibitory activities. α-Mela...

    Kyong-Suk **, Ji Young Lee, Sook Kyung Hyun… in Food Science and Biotechnology (2015)

  2. No Access

    Article

    Angiotensin converting enzyme inhibitory benzopyranoids from Angelica gigas

    Angiotensin converting enzyme (ACE) plays a major role in the regulation of blood pressure. The potential antihypertensive activity of Angelica gigas was evaluated in vitro by its ability to inhibit ACE. A methan...

    Sook Kyung Hyun, You Na Oh, Hyun Ju Kwon, Byung Woo Kim in Food Science and Biotechnology (2013)

  3. No Access

    Article

    Widdrol activates DNA damage checkpoint through the signaling Chk2–p53–Cdc25A–p21–MCM4 pathway in HT29 cells

    Widdrol is an odorant compound isolated from Juniperus chinensis. We previously reported that widdrol induces Gap 1 (G1) phase cell cycle arrest and leads to apoptosis in human colon adenocarcinoma HT29 cells. It...

    Hee Jung Yun, Sook Kyung Hyun, Jung Ha Park… in Molecular and Cellular Biochemistry (2012)

  4. No Access

    Article

    In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids fromGingko biloba yellow leaves

    As part of our research on phytochemicals that exert protective effects against diseases related to reactive nitrogen specie, we have evaluated the scavenging activity of the yellow leaves ofGinkgo biloba on ONOO

    Sook Kyung Hyun, Hyun Ah Jung, Hae Young Chung… in Archives of Pharmacal Research (2006)

  5. No Access

    Article

    Angiotensin-converting enzyme I inhibitory activity of phlorotannins from Ecklonia stolonifera

    As part of our study of the isolation of antihypertensive agents derived from natural marine products, the bioactivity of 10 edible Korean seaweeds were screened by angiotensin converting enzyme (ACE) inhibito...

    Hyun Ah Jung, Sook Kyung Hyun, Hyeung Rak Kim, Jae Sue Choi in Fisheries Science (2006)

  6. No Access

    Article

    Isorhamnetin glycosides with free radical and ONOO− scavenging activities from the stamens ofNelumbo nucifera

    In this study, we isolated two new isorhamnetin glycosides, designated as nelumboroside A (3) and nelumboroside B (4), as well as the previously-characterized isorhamnetin glucoside (1) and isorhamnetin rutinosid...

    Sook Kyung Hyun, Yu Jung Jung, Hae Young Chung… in Archives of Pharmacal Research (2006)

  7. No Access

    Article

    A phenolic glucoside isolated fromPrunus serrulata var.spontanea and its peroxynitrite scavenging activity

    A new phenolic glucoside (1), pursargentoside, was isolated from the leaves ofPrunus serrulata var.spontanea, along with three other known compounds, orobol 7-O-glucoside (2), 1β, 2α, 3α, 24-tetrahydroxy-urs-12-e...

    Hyun Ah Jung, Hae Young Chung, Sam Sik Kang… in Archives of Pharmacal Research (2005)

  8. No Access

    Article

    In Vitro Free Radical and ONOO- Scavengers from Sophora flavescens

    Activity-guided fractionation of the CH2CI2-soluble fraction of the roots of Sophora flavescens furnished five 1,1 -diphenyl-2-picrylhydrazyl (DPPH) free radical scavengers: trans-hexadecyl ferulic acid (1), cis-...

    Hee ** Jung, Sam Sik Kang, Sook Kyung Hyun, Jae Sue Choi in Archives of Pharmacal Research (2005)

  9. No Access

    Article

    Alaternin and emodin with hydroxyl radical inhibitory and/or scavenging activities and hepatoprotective activity on tacrine-induced cytotoxicity in HepG2 cells

    The antioxidative and hepatoprotective potentials of two anthraquinones, alaternin (2-hydroxy-emodin) and emodin, to scavenge and/or inhibit hydroxyl radicals generated by the Fenton reaction and to protect ta...

    Hyun Ah Jung, Hae Young Chung, Takako Yokozawa… in Archives of Pharmacal Research (2004)