2 Result(s)

Article

L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial

The chemokine CXCL12 promotes glioblastoma (GBM) recurrence after radiotherapy (RT) by facilitating vasculogenesis. Here we report outcomes of the dose-escalation part of GLORIA (NCT04121455), a phase I/II tri...

Frank A. Giordano, Julian P. Layer, Sonia Leonardelli… in Nature Communications (2024)

Article

A pan-cancer fingerprint: common molecular denominators of the human tumor microenvironment

Susanna S. Ng, Sonia Leonardelli… in Signal Transduction and Targeted Therapy (2021)