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Article
Lineage tracking reveals dynamic relationships of T cells in colorectal cancer
T cells are key elements of cancer immunotherapy1 but certain fundamental properties, such as the development and migration of T cells within tumours, remain unknown. The enormous T cell receptor (TCR) repertoire...
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Article
Open AccessBRAFV600E status and clinical characteristics in solitary and multiple papillary thyroid carcinoma: experience of 512 cases at a clinical center in China
Papillary thyroid carcinoma (PTC) is one of the most frequent endocrine malignancies. In most cases, it often presents as multifocal tumor. It has been reported that multifocal tumors are associated with eleva...
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Article
Open AccessBMP-6 promotes E-cadherin expression through repressing δEF1 in breast cancer cells
Bone morphogenetic protein-6 (BMP-6) is critically involved in many developmental processes. Recent studies indicate that BMP-6 is closely related to tumor differentiation and metastasis.
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Article
PGC-1α induces apoptosis in human epithelial ovarian cancer cells through a PPARγ-dependent pathway
Peroxisome proliferator-activated receptor gamma (PPARγ) coactivator-1 alpha (PGC-1α) coactivates multiple transcription factors and regulates several metabolic processes. The current study investigated the ro...
