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  1. Article

    Open Access

    Cardiac-to-adipose axis in metabolic homeostasis and diseases: special instructions from the heart

    Adipose tissue is essential for maintaining systemic metabolic homeostasis through traditional metabolic regulation, endocrine crosstalk, and extracellular vesicle production. Adipose dysfunction is a risk fac...

    Songling Tang, Ruixin Li, Wen Ma, Liu Lian, Jiuyu Gao, Yu Cao, Lu Gan in Cell & Bioscience (2023)

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  2. Article

    Open Access

    CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice

    CD38 is the main enzyme for nicotinamide adenine dinucleotide (NAD) degradation in mammalian cells. Decreased NAD levels are closely related to metabolic syndromes and aging-related diseases. Our study showed ...

    Lu Gan, Demin Liu, **g Liu, Erya Chen… in Signal Transduction and Targeted Therapy (2021)

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