22 Result(s)

Article

Retraction Note: Circular RNA circStag1 promotes bone regeneration by interacting with HuR

Gaoyang Chen, Canling Long, Shang Wang, Zhenmin Wang, **n Chen, Wanze Tang… in Bone Research (2024)

Article

CMTM6 as a potential therapy target is associated with immunological tumor microenvironment and can promote migration and invasion in pancreatic adenocarcinoma

CMTM6 has been connected to the development of several malignancies. However, it is still unknown what function CMTM6 serves in pancreatic adenocarcinoma (PAAD). We obtained RNA sequencing information of PAAD ...

Hongli Gao, Jianqiao Yin, **n Guan, Shuang Zhang… in Functional & Integrative Genomics (2023)

Article

RETRACTED ARTICLE: Circular RNA circStag1 promotes bone regeneration by interacting with HuR

Postmenopausal osteoporosis is a common bone metabolic disorder characterized by deterioration of the bone microarchitecture, leading to an increased risk of fractures. Recently, circular RNAs (circRNAs) have ...

Gaoyang Chen, Canling Long, Shang Wang, Zhenmin Wang, **n Chen, Wanze Tang… in Bone Research (2022)

Article

Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis

Bone morphogenetic protein (BMP) signaling is essential for osteogenesis. However, recombinant human BMPs (rhBMPs) exhibit large inter-individual variations in local bone formation during clinical spinal fusio...

Chao Liang, Songlin Peng, Jie Li, Jun Lu, Daogang Guan, Feng Jiang… in Nature Communications (2018)

Article

Novel biomaterial strategies for controlled growth factor delivery for biomedical applications

Growth factors (GFs) are soluble proteins secreted by cells that have the ability to regulate a variety of cellular processes and tissue regeneration. However, their translation into clinical applications is l...

Zhenming Wang, Zhefeng Wang, William Weijia Lu, Wanxin Zhen… in NPG Asia Materials (2017)

Article

TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis

Pneumoconiosis, caused by inhalation of mineral dusts, is a major occupational disease worldwide. Currently, there are no effective drugs owing to a lack of potential therapeutic targets during either the infl...

Jie Li, Chao Liang, Zong-Kang Zhang, **aohua Pan, Songlin Peng… in Cell Discovery (2017)

Article

Targeting osteoblastic casein kinase-2 interacting protein-1 to enhance Smad-dependent BMP signaling and reverse bone formation reduction in glucocorticoid-induced osteoporosis

The underlying mechanism of the reduced bone formation during the development of glucocorticoid-induced osteoporosis (GIO) remains unclear. Here, we found that the highly expressed CKIP-1 together with lowly e...

** Liu, Changwei Lu, **aohao Wu, Zongkang Zhang, Jie Li… in Scientific Reports (2017)

Article

Osteoclastic miR-214 targets TRAF3 to contribute to osteolytic bone metastasis of breast cancer

The role of osteoclastic miRNAs in regulating osteolytic bone metastasis (OBM) of breast cancer is still underexplored. Here, we examined the expression profiles of osteoclastogenic miRNAs in human bone specim...

** Liu, Defang Li, Lei Dang, Chao Liang, Baosheng Guo, Cheng Lu… in Scientific Reports (2017)

Article

Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation

Emerging evidence indicates that osteoclasts direct osteoblastic bone formation. MicroRNAs (miRNAs) have a crucial role in regulating osteoclast and osteoblast function. However, whether miRNAs mediate osteocl...

Defang Li, ** Liu, Baosheng Guo, Chao Liang, Lei Dang, Cheng Lu… in Nature Communications (2016)

Article

Src inhibitor reduces permeability without disturbing vascularization and prevents bone destruction in steroid-associated osteonecrotic lesions in rabbits

To examine the therapeutic effect of Src inhibitor on the VEGF mediating vascular hyperpermeability and bone destruction within steroid-associated osteonecrotic lesions in rabbits. Rabbits with high risk for p...

Yi-**n He, ** Liu, Baosheng Guo, Yi-**ang Wang, … in Scientific Reports (2015)

Article

Levels of neuropeptide Y in synovial fluid relate to pain in patients with knee osteoarthritis

The precise etiology of knee osteoarthritis (KOA) pain remains highly controversial and there is no known effective treatment. Due to the known and suggested effects of neuropeptide Y (NPY) on pain, we have so...

Lei Wang, Li Zhang, Haobo Pan, Songlin Peng, Minmin Lv… in BMC Musculoskeletal Disorders (2014)

Article

Resection of a malignant paraganglioma located behind the retrohepatic segment of the inferior vena cava

Resection of a retrocaval paraganglioma is technically challenging due to limited tumor accessibility and proximity to the vena cava.

Changjun Jia, **nlu Wang, Chaoliu Dai, **anmin Bu, Songlin Peng, Feng Xu… in BMC Surgery (2013)

Article

Undifferentiated embryonal sarcoma of the liver in a middle-aged adult with systemic lupus erythematosus

Adult primary undifferentiated embryonal sarcoma of the liver (UESL) is a rare disease. While the etiology of UESL remains largely unknown, association with systemic inflammatory disorders has been observed. H...

Changjun Jia, Wei Zhao, Chaoliu Dai, **nlu Wang… in World Journal of Surgical Oncology (2013)

Article

The role of hepatocyte nuclear factor 4alpha in metastatic tumor formation of hepatocellular carcinoma and its close relationship with the mesenchymal–epithelial transition markers

Mesenchymal–epithelial transition (MET) is now suggested to participate in the process of metastatic tumor formation. However, in hepatocellular carcinoma (HCC) the process is still not well revealed.

Dianbo Yao, Songlin Peng, Chaoliu Dai in BMC Cancer (2013)