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  1. Article

    Open Access

    Seroprevalence of herpes simplex virus type 1 and type 2 among the migrant workers in Qatar

    Limited data exists on herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections in migrant populations. This study investigated HSV-1 and HSV-2 seroprevalences and associations among craft and manual ...

    Gheyath K. Nasrallah, Soha R. Dargham, Duaa W. Al-Sadeq in Virology Journal (2023)

  2. Article

    Open Access

    Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population

    Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 “ever” (past or current) infection in a population-based sample in a high exposure setting. PCR ...

    Gheyath K. Nasrallah, Soha R. Dargham, Farah Shurrab in Scientific Reports (2021)

  3. Article

    Open Access

    A diabetes risk score for Qatar utilizing a novel mathematical modeling approach to identify individuals at high risk for diabetes

    We developed a diabetes risk score using a novel analytical approach and tested its diagnostic performance to detect individuals at high risk of diabetes, by applying it to the Qatari population. A representat...

    Susanne F. Awad, Soha R. Dargham, Amine A. Toumi, Elsy M. Dumit in Scientific Reports (2021)

  4. Article

    Open Access

    Characterizing the type 2 diabetes mellitus epidemic in Jordan up to 2050

    We aimed to characterize the type 2 diabetes mellitus (T2DM) epidemic and the role of key risk factors in Jordan between 1990–2050, and to forecast the T2DM-related costs. A recently-developed population-level...

    Susanne F. Awad, Peijue Huangfu, Soha R. Dargham, Kamel Ajlouni in Scientific Reports (2020)

  5. Article

    Open Access

    Metabolic comparison of polycystic ovarian syndrome and control women in Middle Eastern and UK Caucasian populations

    To determine if metabolic characteristics differed in women with and without polycystic ovary syndrome (PCOS) between a Caucasian and Middle East population. Comparative cross-sectional analysis. Demographic a...

    Alexandra E. Butler, Ahmed Abouseif, Soha R. Dargham in Scientific Reports (2020)

  6. Article

    Open Access

    Vitamin D3 metabolite ratio as an indicator of vitamin D status and its association with diabetes complications

    Vitamin D deficiency is diagnosed by total serum 25-hydroxyvitamin D (25(OH)D) concentration and is associated with poor health and increased mortality; however, some populations have low 25(OH) D concentratio...

    Lina H. M. Ahmed, Alexandra E. Butler, Soha R. Dargham in BMC Endocrine Disorders (2020)

  7. Article

    Open Access

    Association of vitamin D2 and D3 with type 2 diabetes complications

    Vitamin D measurement is a composite of vitamin D2 (25(OH)D2) and D3 (25(OH)D3) levels, and its deficiency is associated with the development of type 2 diabetes (T2DM) and diabetic complications; vitamin D defici...

    Lina H. M. Ahmed, Alexandra E. Butler, Soha R. Dargham in BMC Endocrine Disorders (2020)

  8. Article

    Open Access

    Expression of microRNA in follicular fluid in women with and without PCOS

    Several studies have shown the expression of small non-coding microRNA (miRNA) changes in PCOS and their expression in follicular fluid has been described, though the number of studies remains small. In this p...

    Alexandra E. Butler, Vimal Ramachandran, Shahina Hayat in Scientific Reports (2019)

  9. Article

    Open Access

    Analytical Exploration of Potential Pathways by which Diabetes Mellitus Impacts Tuberculosis Epidemiology

    We aimed to develop a conceptual framework of diabetes mellitus (DM) effects on tuberculosis (TB) natural history and treatment outcomes, and to assess the impact of these effects on TB-transmission dynamics. ...

    Susanne F. Awad, Soha R. Dargham, Ryosuke Omori, Fiona Pearson in Scientific Reports (2019)

  10. Article

    Open Access

    Salivary and serum androgens with anti-Müllerian hormone measurement for the diagnosis of polycystic ovary syndrome

    To determine the predictive value of a raised androgen level with an elevated anti-Müllerian hormone (AMH) for the diagnosis or exclusion of polycystic ovary syndrome (PCOS), a prospective cross-sectional stud...

    Thozhukat Sathyapalan, Ahmed Al-Qaissi, Eric S. Kilpatrick in Scientific Reports (2018)

  11. Article

    Open Access

    Prediabetes and diabetes in a cohort of Qatari women screened for polycystic ovary syndrome

    Polycystic ovary syndrome (PCOS) is associated with an increased risk of type 2 diabetes mellitus (T2DM) but its association with prediabetes and T2DM is unknown in Qatar. A cross sectional analysis of 3,017 Qata...

    Soha R. Dargham, Abeer El Shewehy, Youssra Dakroury in Scientific Reports (2018)

  12. Article

    Open Access

    Circulating microparticles in acute diabetic Charcot foot exhibit a high content of inflammatory cytokines, and support monocyte-to-osteoclast cell induction

    Circulating microparticles (MPs) are major mediators in cardiovascular complications of type 2 diabetes (T2D); however, their contribution to Charcot foot (CF) disease is not known. Here, we purified and asses...

    Jennifer Pasquier, Binitha Thomas, Jessica Hoarau-Véchot, Tala Odeh in Scientific Reports (2017)

  13. Article

    Open Access

    Salivary testosterone measurement in women with and without polycystic ovary syndrome

    Clinical and/or biochemical hyperandrogenism is one of the diagnostic criteria for PCOS. An evaluation of the role of salivary testosterone (salT) and androstenedione (salA) for the diagnosis of PCOS was under...

    Thozhukat Sathyapalan, Ahmed Al-Qaissi, Eric S. Kilpatrick in Scientific Reports (2017)