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Article
Open AccessBDNF belongs to the nurse-like cell secretome and supports survival of B chronic lymphocytic leukemia cells
Evading apoptosis and sustained survival signaling pathways are two central hallmarks of B-cell chronic lymphocytic leukemia (B-CLL) cells. In this regard, nurse-like cells (NLC), the monocyte-derived type 2 m...
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Article
Open AccessAnti-apoptotic role and clinical relevance of neurotrophins in diffuse large B-cell lymphomas
Diffuse large B-cell lymphoma (DLBCL) is a fatal malignancy that needs to identify new targets for additional therapeutic options. This study aimed to clarify the clinical and biological significance of endoge...
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Article
Open AccessNeurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling
Giant cell arteritis (GCA) is characterized by intimal hyperplasia leading to ischaemic manifestations that involve large vessels. Neurotrophins (NTs) and their receptors (NTRs) are protein factors for growth,...