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  1. Article

    Open Access

    Two-dimensional temperature-responsive chromatography using a poly(N-isopropylacrylamide) brush-modified stationary phase for effective therapeutic drug monitoring

    Therapeutic drug monitoring (TDM) is an effective pharmacological approach for controlling drug concentration in a patient’s serum. Herein, a new two-dimensional chromatography system was developed using two p...

    Kenichi Nagase, So Inoue, Masakazu Inoue, Hideko Kanazawa in Scientific Reports (2022)