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Article
Open AccessTwo-dimensional temperature-responsive chromatography using a poly(N-isopropylacrylamide) brush-modified stationary phase for effective therapeutic drug monitoring
Therapeutic drug monitoring (TDM) is an effective pharmacological approach for controlling drug concentration in a patient’s serum. Herein, a new two-dimensional chromatography system was developed using two p...
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Article
A new approach to dynamic graciloplasty
The reestablishment of anal function by transposition of the gracilis muscle, combined with the implantation of electrodes and a neuromuscular stimulator (dynamic graciloplasty), has recently been developed. ...
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Negative Growth Regulation of Oncogene-Transformed Mammary Epithelial Cells by Tumor Inhibitors
Deregulated expression of Ras and myc oncogenes confers neoplastic transformation in non-tumorigenic mammary epithelial cells. Down-regulation of perturbed biomarkers prior to tumorigenesis may provide a means...
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Article
Human breast carcinoma (ZR-75-1) serially transplanted into nude mice-with reference to estradiol dependency and sensitivity to tamoxifen
Tumor cells of the ZR-75-1 line (1×107 in 0.5 ml) were inoculated into the right thigh muscles of BALB/c female nude mice which were, at the same time, given 1.0 mg of estradiol subcutaneously. After the transfer...