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Article
Cytotoxic epipolythiodioxopiperazine alkaloids from filamentous fungi of the Bionectriaceae
Bioactivity-directed fractionation of the organic extracts of two filamentous fungi of the Bionectriaceae, strains MSX 64546 and MSX 59553 from the Mycosynthetix library, led to the isolation of a new dimeric ...
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Article
Cytotoxic xanthone–anthraquinone heterodimers from an unidentified fungus of the order Hypocreales (MSX 17022)
Two new xanthone–anthraquinone heterodimers, acremoxanthone C (5) and acremoxanthone D (2), have been isolated from an extract of an unidentified fungus of the order Hypocreales (MSX 17022) by bioactivity-directe...
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Article
Anthelmintic constituents of Clonostachys candelabrum
Five diastereomeric polyketide glycosides, roselipins 3A-3E (1–5), have been isolated from the acetone extract of Clonostachys candelabrum on the basis of their positive anthelmintic activity. The structures of t...
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Article
Anthelmintic Macrolactams from Nonomuraea turkmeniaca MA7381
A new macrolactam, fluvirucin B0 (1), and two known macrolactams, Sch 38516/fluvirucin B1 (2) and Sch 39185/fluvirucin B3 (3), have been isolated from an acetone extract of a strain of Nonomuraea turkmeniaca. The...
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Article
A pH-Stability Study of Phoslactomycin B and Analysis of the Acid and Base Degradation Products
Phoslactomycin B (PLM-B), a potent and selective inhibitor of serine threonine phosphatase is of interest for its antitumor, antifungal and antiviral activity. Described herein is an evaluation of the solution...