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  1. Article

    Role of the cGAS–STING pathway in systemic and organ-specific diseases

    Cells are equipped with numerous sensors that recognize nucleic acids, which probably evolved for defence against viruses. Once triggered, these sensors stimulate the production of type I interferons and other...

    Sladjana Skopelja-Gardner, Jie An, Keith B. Elkon in Nature Reviews Nephrology (2022)

  2. Article

    Open Access

    The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent

    Most systemic lupus erythematosus (SLE) patients are photosensitive and ultraviolet B light (UVB) exposure worsens cutaneous disease and precipitates systemic flares of disease. The pathogenic link between ski...

    Sladjana Skopelja-Gardner, Jie An, Joyce Tai, Lena Tanaka in Scientific Reports (2020)