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    Article

    Assessing and engineering the IscB–ωRNA system for programmed genome editing

    OMEGA RNA (ωRNA)-guided endonuclease IscB, the evolutionary ancestor of Cas9, is an attractive system for in vivo genome editing because of its compact size and mechanistic resemblance to Cas9. However, wild-t...

    Hao Yan, **aoqing Tan, Siyuan Zou, Yihong Sun, Ailong Ke in Nature Chemical Biology (2024)

  2. Article

    Author Correction: An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity

    Tong Wu, Chang Liu, Siyuan Zou, Ruitu Lyu, Bowei Yang, Hao Yan in Nature Chemical Biology (2024)

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    Article

    An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity

    Compact CRISPR-Cas systems offer versatile treatment options for genetic disorders, but their application is often limited by modest gene-editing activity. Here we present enAsCas12f, an engineered RNA-guided ...

    Tong Wu, Chang Liu, Siyuan Zou, Ruitu Lyu, Bowei Yang, Hao Yan in Nature Chemical Biology (2023)

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    Article

    Adaptive two-filter smoothing based on second-order divided difference filter for distributed position and orientation system

    The distributed position and orientation system (POS) uses transfer alignment to accurately measure multi-node time-spatial reference information, which is necessary for compensating the motion error of imagin...

    Jianli Li, Siyuan Zou, Bin Gu, Jiancheng Fang in Science China Information Sciences (2019)

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    Article

    Semiautomatic Structures

    Semiautomatic structures generalise automatic structures in the sense that for some of the relations and functions in the structure one only requires the derived relations and functions are automatic when all ...

    Sanjay Jain, Bakhadyr Khoussainov, Frank Stephan, Dan Teng in Theory of Computing Systems (2017)

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    Article

    Estimating the parental magma composition and temperature of the **aohaizi cumulate-bearing ultramafic rock: Implication for magma evolution of the Tarim large igneous province, northwestern China

    The ultramafic dikes in the Tarim large igneous province (Tarim LIP), exposed in the **aohaizi area in the northwestern Tarim Basin of northwestern China, have porphyritic textures, and the olivine and clinopy...

    Haowei Sun, Yinqi Li, Zilong Li, Siyuan Zou in Journal of Earth Science (2016)

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    Chapter and Conference Paper

    Semiautomatic Structures

    Semiautomatic structures generalise automatic structures in the sense that for some of the relations and functions in the structure one only requires the derived relations and structures are automatic when all...

    Sanjay Jain, Bakhadyr Khoussainov in Computer Science - Theory and Applications (2014)