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Article
Open AccessGeneration of tissues outside the field of view (FOV) of radiation therapy simulation imaging based on machine learning and patient body outline (PBO)
It is not unusual to see some parts of tissues are excluded in the field of view of CT simulation images. A typical mitigation is to avoid beams entering the missing body parts at the cost of sub-optimal plann...
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Article
Open AccessRadiotherapy-Compatible Robotic System for Multi-Landmark Positioning in Head and Neck Cancer Treatments
The spine flexibility creates one of the most significant challenges to proper positioning in radiation therapy of head and neck cancers. Even though existing immobilization techniques can reduce the positioni...
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Article
Open AccessModeling scattered radiation from multi-leaf collimators (MLCs) to improve calculation accuracy of in-air output ratio
This study aims to model an extra-focal source for the scattered radiation from multi-leaf collimators (MLCs), namely an MLC scatter source, and to correct in-air output ratio (Sc) calculated using the convention...
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Article
Open AccessTo propose adding index of achievement (IOA) to IMRT QA process
In intensity modulated radiation therapy (IMRT) quality assurance (QA), evaluation of QA result using a pass/non-pass strategy under an acceptance criterion often suffers from lack of information on how good t...
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Article
Open AccessSuperresolution fluorescence microscopy for 3D reconstruction of thick samples
Three-dimensional (3D) reconstruction of thick samples using superresolution fluorescence microscopy remains challenging due to high level of background noise and fast photobleaching of fluorescence probes. We...
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Article
The effect of beam interruption during FFF-VMAT plans for SBRT
To investigate the dosimetric effect of intended beam interruption during volumetric modulated arc therapy (VMAT) with flattening filter free (FFF) beam for exploring the possibility of deep inspiration breath...
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Article
Open AccessPKCα-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memory
Lysine-specific demethylase 1 (LSD1) is a histone demethylase that participates in transcriptional repression or activation. Recent studies reported that LSD1 is involved in learning and memory. Although LSD1 ...
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Article
Technical note: real-time web-based wireless visual guidance system for radiotherapy
Describe a Web-based wireless visual guidance system that mitigates issues associated with hard-wired audio-visual aided patient interactive motion management systems that are cumbersome to use in routine clin...
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Article
A noble technique a using force-sensing resistor for immobilization-device quality assurance: A feasibility study
Many studies have reported that a patient can move even when an immobilization device is used. Researchers have developed an immobilization-device quality-assurance (QA) system that evaluates the validity of i...
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Article
Feasibility study of patient motion monitoring by using tactile array sensors
An ideal alignment method based on the external anatomical surface of the patient should consider the entire region of interest. However, optical-camera-based systems cannot blindly monitor such areas as the p...
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Article
Development of a beam stop array system with dual scan mode for scatter correction of cone-beam CT
A beam stop array (BSA) is widely used to estimate the scatter distribution of cone-beam computed tomography (CT) experimentally. A rectangular BSA, which is the most generally used, produces a penumbra region...
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Article
Open AccessOptimal set of grid size and angular increment for practical dose calculation using the dynamic conformal arc technique: a systematic evaluation of the dosimetric effects in lung stereotactic body radiation therapy
To recommend the optimal plan parameter set of grid size and angular increment for dose calculations in treatment planning for lung stereotactic body radiation therapy (SBRT) using dynamic conformal arc therap...
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Chapter and Conference Paper
Is Dosimetric Effect of Leaf Width of MLC Clinically Significant in IMRT
It is generally believed that the quality of intensity modulated radiation therapy (IMRT) treatment plans with finer multi-leaf collimator (MLC) leaf resolution is better. We tested this hypothesis by analyzin...
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Chapter and Conference Paper
A new paradigm of IMRT plan evaluation with uncertainty volume histogram
In intensity-modulated radiotherapy (IMRT), it is common to compare different treatment plans and choose the optimal one. Current plan evaluation methods include side-by-side dose comparisons with isodose line...
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Chapter and Conference Paper
IMRT dose verification using the dose uncertainty prediction model
Intensity modulated radiation therapy (IMRT) has been introduced to conform to a three-dimensional (3-D) shape of a tumor with a custom tailored radiation dose while protecting surrounding normal tissues. The ...
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Chapter and Conference Paper
Imaging linear accelerator output using a high-speed scintillation based electronic portal imaging device (Hi-EPID)
We have developed a high-speed scintillation based electronic portal imaging device (Hi-EPID) to image the fluence output of a linear accelerator as it exits the head. The Hi-EPID consists of a high speed digi...
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Chapter and Conference Paper
Measurement of One-dimensional Photon Dose Distribution in Radiotherapy Dosimetry Using a High-resolution Fiber-optic Radiation Sensor
The purpose of this study is to develop a method for measuring the one-dimensional dose distribution of high-energy photon beam using a miniaturized highresolution fiber-optic radiation sensor array. The measu...
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Chapter and Conference Paper
Characterizations of Cerenkov Radiation in Fiber-optic Radiation Sensor for High Energy Electron Beam Therapy Dosimetry
In this study, a fiber-optic radiation sensor has been developed using a small, water-equivalent organic scintillator for electron beam therapy dosimetry. Usually, two kinds of light signals such as fluorescen...
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Chapter and Conference Paper
A Systematic Analysis of IMRT QA Results
A commercial 2-D diode array (Mapcheck, Sun Nuclear) has been used for IMRT plan QA at the University of Florida. By retrospectively reviewing the QA data we have systematically evaluated factors that influenc...