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Article
Hypotensive episodes at 24-h ambulatory blood pressure monitoring predict adverse outcomes in Parkinson’s disease
Neurogenic orthostatic hypotension (nOH) is a frequent nonmotor feature of Parkinson’s disease (PD), associated with adverse outcomes. Recently, 24-h ambulatory blood pressure monitoring (ABPM) showed good acc...
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Article
Open AccessBurden of caregiving for cardiovascular dysautonomia in Parkinson’s disease
We sought to estimate the impact of cardiovascular autonomic neuropathy (cAN) on informal caregivers of patients with Parkinson’s disease (PD), defined as individuals providing regular care to a friend, partne...
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Article
Open AccessDifferential impact of individual autonomic domains on clinical outcomes in Parkinson’s disease
While autonomic failure is a well-known prognostic factor for more aggressive disease progression in Parkinson’s disease (PD), with a three- to sevenfold higher risk of dementia and death within 10 years after...
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Article
Kinematic but not clinical measures predict falls in Parkinson-related orthostatic hypotension
We sought to test the hypothesis that technology could predict the risk of falls in Parkinson’s disease (PD) patients with orthostatic hypotension (OH) with greater accuracy than in-clinic assessment.
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Article
Detection of orthostatic hypotension with ambulatory blood pressure monitoring in parkinson’s disease
We sought to test the accuracy of 24-hours ambulatory blood pressure (BP) monitoring (ABPM) for the detection of orthostatic hypotension (OH) in Parkinson’s disease (PD). A total of 113 patients referred for a...
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Article
Blood pressure circadian rhythm alterations in alpha-synucleinopathies
We sought to analyze the blood pressure (BP) circadian rhythm in Parkinson’s disease (PD), multiple system atrophy (MSA), and pure autonomic failure (PAF) and to evaluate the effect of vasoactive and dopaminer...
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Article
Cardiovascular autonomic neuropathy and falls in Parkinson disease: a prospective cohort study
Falls represent one of the main complications of Parkinson’s disease (PD), significantly lowering quality of life. Cardiovascular autonomic neuropathy (cAN) is one of the key contributing factors to PD-associa...
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Article
Treatment of supine hypertension in autonomic failure: a case series
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Article
Cardiovascular complications in patients with autonomic failure
Patients with autonomic failure are characterized by orthostatic hypotension, supine hypertension, high blood pressure variability, blunted heart rate variability, and often have a “non-dip**” or “reverse di...
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Article
Arrhythmic syncope in neurogenic orthostatic hypotension: two case reports
Patients with autonomic failure experience orthostatic hypotension (OH) often leading to syncope. Arrhythmias may cause severe syncope, characterized by an increased risk of mortality. We report two cases of p...
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Article
Neurogenic orthostatic hypotension as the initial feature of Parkinson disease
Autonomic failure is a common finding in patients with Parkinson disease (PD). Here we describe a patient with PD in whom autonomic symptoms began 3 years before motor deficits.
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Article
Ventricular repolarization before and after treatment in patients with secondary hypertension due to renal-artery stenosis and primary aldosteronism
A prolonged QT interval is a risk factor for ischemic heart disease in hypertensive subjects. Patients with renal-artery stenosis and primary aldosteronism (PA) are at increased risk of cardiovascular events. ...
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Article
Prolonged QT Interval and Reduced Heart Rate Variability in Patients with Uncomplicated Essential Hypertension
A prolonged QT interval is a risk factor for ischemic heart disease in hypertensive subjects. Heart rate variability (HRV) is both an index of autonomic function and an important prognostic factor in several d...
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Article
Sympathetic hyperactivity in patients with ulcerative colitis
Hypo and hyperactivity of the autonomic nervous system have been associated with chronic bowel inflammation diseases. We investigated the autonomic function in 11 patients with chronic ulcerative colitis (UC) ...
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Article
Helicobacter pylori infection and gastric function in primary autonomic neuropathy
Helicobacter pylori (Hp) infection in diabetic patients has been related to impaired gastric clearance of bacteria due to autonomic neuropathy. Gastrointestinal dysfunction has been described in primary autonomi...
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Article
The effects of exposure to moderate altitude on cardiovascular autonomic function in normal subjects
Cardiovascular responses to altitude have been studied on well-trained young subjects, generally at high altitudes (>4000 m). Less known are the effects of exposure to lower altitudes, easily reached by the ge...