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Article
Reward motivation adaptation in people with negative schizotypal features: development of a novel behavioural paradigm and identifying its neural correlates using resting-state functional connectivity analysis
Reward motivation in individuals with high levels of negative schizotypal traits (NS) has been found to be lower than that in their counterparts. But it is unclear that whether their reward motivation adaptive...
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Article
Open AccessAuthor Correction: The network characteristics in schizophrenia with prominent negative symptoms: a multimodal fusion study
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Article
Open AccessThe network characteristics in schizophrenia with prominent negative symptoms: a multimodal fusion study
Previous studies on putative neural mechanisms of negative symptoms in schizophrenia mainly used single modal imaging data, and seldom utilized schizophrenia patients with prominent negative symptoms (PNS).Thi...
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Article
A transdiagnostic network analysis of motivation and pleasure, expressivity and social functioning
Negative symptoms, comprising the motivation and pleasure (MAP) factor and the expressivity (EXP) factor, are key determinants of social functioning in schizophrenia (SCZ). Although negative symptoms are also ...
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Article
Altered neural mechanism of social reward anticipation in individuals with schizophrenia and social anhedonia
Altered social reward anticipation could be found in schizophrenia (SCZ) patients and individuals with high levels of social anhedonia (SA). However, few research investigated the putative neural processing fo...
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Article
Impact of restrictive COVID-19 measures on daily momentary affect in an epidemiological youth sample in Hong Kong: An experience sampling study
Restrictive COVID-19 measures can have significant mental health impacts, particularly on young people. How such measures may influence day-to-day momentary affect, nonetheless, remains to be explored. Experie...
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Article
Open AccessUnveiling common psychological characteristics of proneness to aggression and general psychopathology in a large community youth cohort
Elevated aggression in individuals with psychiatric disorders is frequently reported yet aggressive acts among people with mental illness are often intertwined with proneness to aggression and other risk facto...
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Article
Relationship Between Interoception and Autistic Traits: A Resting-State Functional Connectivity Study
Interoception, the sense of the physiological condition of our body, is impaired in individuals with autism spectrum disorders. Evidence suggests that subclinical autistic traits are mild manifestations of aut...
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Article
Psychometric Properties of the Caregiver Strain Questionnaire in a Chinese Sample of Caregivers of Children with Autism Spectrum Disorder
The Caregiver Strain Questionnaire assesses the three dimensions of caregiver strain, namely the objective, subjective externalized and subjective internalized strain. It was validated among caregivers of chil...
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Article
Open AccessProspection deficits in patients with first-episode schizophrenia: a cross-sectional comparative study
Prospection refers to the ability to simulate and pre-experience future events. Schizophrenia patients have difficulty in anticipating pleasure in future events, but previous studies examined prospection defic...
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Article
Bridge centrality network structure of negative symptoms in people with schizophrenia
Negative symptoms are complex psychopathology. Although evidence generally supported the NIMH five consensus domains, research seldom examined measurement invariance of this model, and domain-specific correspo...
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Article
Negative schizotypal traits predict the reduction of reward motivation in effort–reward imbalance
The schizotypy construct is useful for studying the effects of environmental stress on development of subclinical negative symptoms. The relationship among self-report motivation, effort–reward imbalance (ERI)...
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Article
The Interplay Between Addictive Behaviour and Psychopathology and Personality in Substance Use Disorder: a Network Analysis in Treatment-Seeking Patients with Alcohol and Drug Use
Substance use disorder (SUD) is characterized by alcohol and drug use, dependence features and adverse psychosocial consequences. SUD represents an interplay between substance use, personality, impulsivity and...
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Article
Open AccessAudiovisual temporal processing in adult patients with first-episode schizophrenia and high-functioning autism
Schizophrenia and autism spectrum disorder (ASD) are both neurodevelopmental disorders with altered sensory processing. Widened temporal binding window (TBW) signifies reduced sensitivity to detect stimulus as...
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Article
Hub-connected functional connectivity within social brain network weakens the association with real-life social network in schizophrenia patients
Hubs in the brain network are the regions with high centrality and are crucial in the network communication and information integration. Patients with schizophrenia (SCZ) exhibit wide range of abnormality in t...
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Article
Shared and distinct reward neural mechanisms among patients with schizophrenia, major depressive disorder, and bipolar disorder: an effort-based functional imaging study
Unwillingness to exert effort for rewards has been found in patients with schizophrenia (SCZ), major depressive disorder (MDD), and bipolar disorder (BD), but the underlying shared and distinct reward neural m...
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Article
Theories and models of negative symptoms in schizophrenia and clinical implications
Negative symptoms in schizophrenia include avolition, anhedonia, asociality, alogia and affective blunting. These symptoms correlate strongly with clinical and functional outcomes, but respond poorly to conven...
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Article
Altered empathy-related resting-state functional connectivity in patients with bipolar disorder
Empathy is the ability to generate emotional responses (i.e., cognitive empathy) and to make cognitive inferences (i.e., affective empathy) to other people’s emotions. Empirical evidence suggests that patients...
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Article
Individuals with Autistic Traits Exhibit Heightened Alexithymia But Intact Interoceptive-Exteroceptive Sensory Integration
Interoceptive accuracy has been widely measured using the Heartbeat Tracking Test (HTT). We devised the novel paradigm of Interoception-Exteroception Synchronicity Judgement (IESJ) task to assess participants’...
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Article
Multidimensional Interoception and Autistic Traits Across life Stages: Evidence From a Novel Eye-tracking Task
Interoception is believed to underlie socio-cognitive functions which are often impaired in individuals with autism spectrum disorders (ASD). In this study, Experiment 1 examined in a sample of 114 neurotypica...
