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    Article

    Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

    Reprogramming cells towards pluripotency by expression of Oct4, Sox2, Klf4 and c-Myc can be directed towards cardiogenesis by changing the cell culture medium, leading to the formation of spontaneously contrac...

    Jem A. Efe, Simon Hilcove, Janghwan Kim, Hongyan Zhou, Kunfu Ouyang in Nature Cell Biology (2011)

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    A chemical platform for improved induction of human iPSCs

    A cocktail of three small molecules improves the efficiency of reprogramming human fibroblasts to induced pluripotent stem cells and allows survival of the cells after trypsinization.

    Tongxiang Lin, Rajesh Ambasudhan, Xu Yuan, Wenlin Li, Simon Hilcove in Nature Methods (2009)