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Open AccessMetabolomic profile of systemic sclerosis patients
Systemic sclerosis (SSc) is an autoimmune disease of unknown aetiology characterized by vascular lesions, immunological alterations and diffuse fibrosis of the skin and internal organs. Since recent evidence s...
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Open AccessGut microbiota profile in systemic sclerosis patients with and without clinical evidence of gastrointestinal involvement
Recent evidence suggests that there is a link between the gut microbial community and immune-mediated disorders. Systemic sclerosis (SSc) is an autoimmune disease characterized by immunonological abnormalities...
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Oxidative stress and the pathogenesis of scleroderma: the Murrell’s hypothesis revisited
Systemic sclerosis (SSc, scleroderma) is a devastating, immune-mediated, multisystem disorder characterized by microvasculature damage, circulating autoantibodies, and fibroblast activation, leading to massive...