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    Article

    Serum levels of anti-heat shock protein 27 antibodies in patients with chronic liver disease

    Heat shock protein 27 (HSP27), an intracellular molecular chaperone, is involved in the pathogenesis of cancer by promoting both tumor cell proliferation and resistance to therapy. HSP27 is also present in the...

    Gabriella Gruden, Patrizia Carucci, Federica Barutta in Cell Stress and Chaperones (2021)

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    Open Access

    NTproBNP in insulin-resistance mediated conditions: overweight/obesity, metabolic syndrome and diabetes. The population-based Casale Monferrato Study

    NTproBNP and BNP levels are reduced in obese subjects, but population-based data comparing the pattern of this relationship in the full spectrum of insulin-resistance mediated conditions, overweight/obesity, m...

    Stefano Baldassarre, Salvatore Fragapani, Antonio Panero in Cardiovascular Diabetology (2017)

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    Article

    Retinal heat shock protein 25 in early experimental diabetes

    Diabetic retinopathy is the leading cause of blindness in adults, and oxidative stress has been pathogenically associated with retinal neurodegeneration. Cellular stresses induce expression of heat shock prote...

    Silvia Pinach, Davina Burt, Elena Berrone, Federica Barutta in Acta Diabetologica (2013)

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    Article

    Serum levels of heat shock protein 27 in patients with acute ischemic stroke

    Expression of intracellular heat shock protein 27 (Hsp27) rises in the brain of animal models of cerebral ischemia and stroke. Hsp27 is also released into the circulation and the aim of the present study was t...

    Gabriella Gruden, Federica Barutta, Irene Catto in Cell Stress and Chaperones (2013)

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    Article

    Circulating anti-Hsp70 levels in nascent metabolic syndrome: the Casale Monferrato Study

    The metabolic syndrome (MetS) confers an increased risk of both type 2 diabetes and cardiovascular diseases (CVD). Heat shock protein 70 (Hsp70), an intracellular polypeptide, can be exposed on the plasma memb...

    Gabriella Gruden, Federica Barutta, Silvia Pinach in Cell Stress and Chaperones (2013)

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    Article

    Serum heat shock protein 27 levels in patients with hepatocellular carcinoma

    Levels of serum heat shock protein 27 (sHsp27) have been studied in numerous cancer types, but their potential relevance in patients with hepatocellular carcinoma (HCC) is undetermined. Our aim was to compare ...

    Gabriella Gruden, Patrizia Carucci, Valentina Lolli in Cell Stress and Chaperones (2013)

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    Article

    Phytosterol-Enriched Yogurt Increases LDL Affinity and Reduces CD36 Expression in Polygenic Hypercholesterolemia

    Dietary enrichment with phytosterols (plant sterols similar to cholesterol) is able to reduce plasma cholesterol levels due to reduced intestinal absorption. The aim of this study was to investigate the effect...

    Gianluca Ruiu, Silvia Pinach, Fabrizio Veglia, Roberto Gambino, Saverio Marena in Lipids (2009)