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Protocol
RNA Editing Detection in HPC Infrastructures
RNA editing by A-to-I deamination is a relevant co/posttranscriptional modification carried out by ADAR enzymes. In humans, it has pivotal cellular effects and its deregulation has been linked to a variety of ...
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Article
Open AccessA gene expression atlas for different kinds of stress in the mouse brain
Stressful experiences are part of everyday life and animals have evolved physiological and behavioral responses aimed at co** with stress and maintaining homeostasis. However, repeated or intense stress can ...
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Article
Open AccessHPC-REDItools: a novel HPC-aware tool for improved large scale RNA-editing analysis
RNA editing is a widespread co-/post-transcriptional mechanism that alters primary RNA sequences through the modification of specific nucleotides and it can increase both the transcriptome and proteome diversi...
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Article
Open AccessELIXIR-IT HPC@CINECA: high performance computing resources for the bioinformatics community
The advent of Next Generation Sequencing (NGS) technologies and the concomitant reduction in sequencing costs allows unprecedented high throughput profiling of biological systems in a cost-efficient manner. Mo...
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Article
Differential Expression of Hippocampal Circular RNAs in the BTBR Mouse Model for Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition with unknown etiology. Recent experimental evidences suggest the contribution of non-coding RNAs (ncRNAs) in the pathophysiology o...
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Article
Open AccessDROPA: DRIP-seq optimized peak annotator
R-loops are three-stranded nucleic acid structures that usually form during transcription and that may lead to gene regulation or genome instability. DRIP (DNA:RNA Immunoprecipitation)-seq techniques are widel...
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Reference Work Entry In depth
Arsenic and microRNA Expression
Arsenic is a naturally occurring metalloid that poses a major threat to worldwide human health. The most toxic form of arsenic is inorganic arsenic, which has been classified by the International Agency for Re...
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Article
Open AccessCoVaCS: a consensus variant calling system
The advent and ongoing development of next generation sequencing technologies (NGS) has led to a rapid increase in the rate of human genome re-sequencing data, paving the way for personalized genomics and prec...
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Living Reference Work Entry In depth
Arsenic and microRNA Expression
Arsenic is a naturally occurring metalloid that poses a major threat to worldwide human health. The most toxic form of arsenic is inorganic arsenic, which has been classified by the International Agency for Re...
