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Article
Open AccessImpact of the 2008 economic crisis on the burden of hepatitis B and C diseases in Southern European countries
The economic crisis that began in 2008 has severely affected Southern (Greece, Italy, Portugal, Spain) Western European (SWE) countries of Western Europe (WE) and may have affected ongoing efforts to eliminate...
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Article
Open AccessScreening for Circulating Inflammatory Proteins Does Not Reveal Plasma Biomarkers of Constant Tinnitus
Tinnitus would benefit from an objective biomarker. The goal of this study is to identify plasma biomarkers of constant and chronic tinnitus among selected circulating inflammatory proteins.
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Article
Open AccessExploring Patterns of Alcohol Consumption in Adolescence: the Role of Health Complaints and Psychosocial Determinants in an Italian Sample
Adolescents are particularly prone to engage in health-risk behaviors such as alcohol and substance use, which can significantly impact their present and future lives. Our study explores the factors contributi...
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Open AccessThe statistical analysis plan for the unification of treatments and interventions for tinnitus patients randomized clinical trial (UNITI-RCT)
Tinnitus is a leading cause of disease burden globally. Several therapeutic strategies are recommended in guidelines for the reduction of tinnitus distress; however, little is known about the potentially incre...
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Article
Open AccessPsychosocial determinants of sleep difficulties in adolescence: the role of perceived support from family, peers, and school in an Italian HBSC sample
The present study explores the concurrent contribution to sleep problems of individual-related, family-related, and school-related factors in adolescence. Gathering from the Italian 2018 Health Behavior in Sch...
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Article
Open AccessTransition to retirement impact on smoking habit: results from a longitudinal analysis within the Survey of Health, Ageing and Retirement in Europe (SHARE) project
In an ageing society, retirement impacts on behavioural risk factors and health outcomes should be carefully assessed. Scant evidence exists from longitudinal studies on the short- and long-term consequences o...
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Article
Open AccessLow Evidence for Tinnitus Risk Factors: A Systematic Review and Meta-analysis
Identifying risk factors for tinnitus could facilitate not only the recommendations for prevention measures, but also identifying potential pathways for new interventions. This study reports the first comprehe...
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Article
Open AccessUsing coding and non-coding rare variants to target candidate genes in patients with severe tinnitus
Tinnitus is the phantom percept of an internal non-verbal set of noises and tones. It is reported by 15% of the population and it is usually associated with hearing and/or brain disorders. The role of structur...
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Article
Open AccessA real world analysis of COVID-19 impact on hospitalizations in older adults with chronic conditions from an Italian region
Healthcare delivery reorganization during the COVID-19 emergency may have had a significant impact on access to care for older adults with chronic conditions. We investigated such impact among all adults with ...
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Article
Open AccessCOVID-19 lockdown impact on familial relationships and mental health in a large representative sample of Italian adults
Benefits of national-level stay-at-home order imposed in Italy to prevent SARS-CoV-2 transmission need to be carefully weighed against its impact on citizens’ health. In a country with a strong familial cultur...
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Open AccessFactors associated with a change in smoking habit during the first COVID-19 lockdown: an Italian cross-sectional study among ever-smokers
The COVID-19 pandemic and the lockdown period lasted from March to May 2020, resulted in a highly stressful situation yielding different negative health consequences, including the worsening of smoking habit.
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Article
Open AccessUse of electronic cigarettes and heated tobacco products during the Covid-19 pandemic
Only a few studies investigated changes in electronic cigarette (e-cigarette) and heated tobacco product (HTP) use during pandemic restrictions. We conducted a web-based cross-sectional study of a representati...
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Article
Open AccessSystematic review and meta-analysis of preclinical studies testing mesenchymal stromal cells for traumatic brain injury
Mesenchymal stromal cells (MSCs) are widely used in preclinical models of traumatic brain injury (TBI). Results are promising in terms of neurological improvement but are hampered by wide variability in treatm...
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Article
Open AccessNational burden of cancer in Italy, 1990–2017: a systematic analysis for the global burden of disease study 2017
We monitored the burden of cancer in Italy and its trends over the last three decades, providing estimates of cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjust...
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Article
Open AccessSleep dissatisfaction and insufficient sleep duration in the Italian population
To investigate the prevalence and possible determinants of sleep quality and quantity, we used data from a cross-sectional study conducted in 2019 on a sample of 3120 subjects, representative of the general It...
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Article
Open AccessHistologic subty** affecting outcome of triple negative breast cancer: a large Sardinian population-based analysis
Triple Negative breast cancer (TNBC) includes a heterogeneous group of tumors with different clinico-pathological features, molecular alterations and treatment responsivity. Our aim was to evaluate the clinico...
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Article
Open AccessRelationship between headaches and tinnitus in a Swedish study
The heterogeneity of tinnitus is likely accounting for the lack of effective treatment approaches. Headaches have been related to tinnitus, yet little is known on how headaches impact tinnitus. We use cross-se...
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Article
Open AccessMap** 123 million neonatal, infant and child deaths between 2000 and 2017
Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to e...
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Article
Worldwide trends in suicide mortality from 1990 to 2015 with a focus on the global recession time frame
To report worldwide trends in suicide mortality during a period that covers 7 years after the 2008 global crisis.
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Article
Open AccessEffect of Tobacco Smoking Cessation on C-Reactive Protein Levels in A Cohort of Low-Dose Computed Tomography Screening Participants
Smokers have higher levels of C-Reactive Protein (CRP) compared to never smokers. The role of smoking cessation on CRP is still under debate. Using data from two screening studies conducted in Italy in 2000–20...
