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Article
Exposure to second-hand smoke and breast cancer risk in non-smoking women: a comprehensive systematic review and meta-analysis
Through the use of an innovative method to identify original publications, we conducted a meta-analysis of all epidemiological studies evaluating the association between second-hand smoke (SHS) exposure and br...
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Article
Open AccessImpact of the 2008 economic crisis on the burden of hepatitis B and C diseases in Southern European countries
The economic crisis that began in 2008 has severely affected Southern (Greece, Italy, Portugal, Spain) Western European (SWE) countries of Western Europe (WE) and may have affected ongoing efforts to eliminate...
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Article
Dose–response association between cigarette smoking and gastric cancer risk: a systematic review and meta-analysis
This study aims at providing an accurate and up-to-date quantification of the dose–response association between cigarette smoking and gastric cancer (GC) risk, overall and by subsite. We conducted a systematic...
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Epidemiology of Tinnitus: Frequency of the Condition
We conducted an umbrella review of the scientific literature followed by a systematic review to comprehensively collect existing evidence on global prevalence from national or regional representative samples o...
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Article
Who are the superheroes? A cross-sectional study on the determinants of good health among Italian older adults
People who reach old age enjoying good physical and mental health can be defined as (health) “superheroes”, given their relatively low impact on healthcare expenditure and the desirable model they represent.
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Open AccessScreening for Circulating Inflammatory Proteins Does Not Reveal Plasma Biomarkers of Constant Tinnitus
Tinnitus would benefit from an objective biomarker. The goal of this study is to identify plasma biomarkers of constant and chronic tinnitus among selected circulating inflammatory proteins.
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Article
Second-hand smoke exposure and cervical cancer: a systematic review and meta-analysis
The association between second-hand smoke (SHS) exposure and cervical cancer (CC) risk is still unclear. The aim of this study is to provide an accurate and updated estimate of this association.
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Article
Open AccessExploring Patterns of Alcohol Consumption in Adolescence: the Role of Health Complaints and Psychosocial Determinants in an Italian Sample
Adolescents are particularly prone to engage in health-risk behaviors such as alcohol and substance use, which can significantly impact their present and future lives. Our study explores the factors contributi...
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Open AccessThe statistical analysis plan for the unification of treatments and interventions for tinnitus patients randomized clinical trial (UNITI-RCT)
Tinnitus is a leading cause of disease burden globally. Several therapeutic strategies are recommended in guidelines for the reduction of tinnitus distress; however, little is known about the potentially incre...
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Article
Open AccessPsychosocial determinants of sleep difficulties in adolescence: the role of perceived support from family, peers, and school in an Italian HBSC sample
The present study explores the concurrent contribution to sleep problems of individual-related, family-related, and school-related factors in adolescence. Gathering from the Italian 2018 Health Behavior in Sch...
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Article
Open AccessTransition to retirement impact on smoking habit: results from a longitudinal analysis within the Survey of Health, Ageing and Retirement in Europe (SHARE) project
In an ageing society, retirement impacts on behavioural risk factors and health outcomes should be carefully assessed. Scant evidence exists from longitudinal studies on the short- and long-term consequences o...
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Article
Open AccessLow Evidence for Tinnitus Risk Factors: A Systematic Review and Meta-analysis
Identifying risk factors for tinnitus could facilitate not only the recommendations for prevention measures, but also identifying potential pathways for new interventions. This study reports the first comprehe...
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Article
Open AccessUsing coding and non-coding rare variants to target candidate genes in patients with severe tinnitus
Tinnitus is the phantom percept of an internal non-verbal set of noises and tones. It is reported by 15% of the population and it is usually associated with hearing and/or brain disorders. The role of structur...
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Article
Open AccessA real world analysis of COVID-19 impact on hospitalizations in older adults with chronic conditions from an Italian region
Healthcare delivery reorganization during the COVID-19 emergency may have had a significant impact on access to care for older adults with chronic conditions. We investigated such impact among all adults with ...
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Article
Open AccessCOVID-19 lockdown impact on familial relationships and mental health in a large representative sample of Italian adults
Benefits of national-level stay-at-home order imposed in Italy to prevent SARS-CoV-2 transmission need to be carefully weighed against its impact on citizens’ health. In a country with a strong familial cultur...
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Open AccessFactors associated with a change in smoking habit during the first COVID-19 lockdown: an Italian cross-sectional study among ever-smokers
The COVID-19 pandemic and the lockdown period lasted from March to May 2020, resulted in a highly stressful situation yielding different negative health consequences, including the worsening of smoking habit.
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Article
Open AccessUse of electronic cigarettes and heated tobacco products during the Covid-19 pandemic
Only a few studies investigated changes in electronic cigarette (e-cigarette) and heated tobacco product (HTP) use during pandemic restrictions. We conducted a web-based cross-sectional study of a representati...
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Article
Open AccessSystematic review and meta-analysis of preclinical studies testing mesenchymal stromal cells for traumatic brain injury
Mesenchymal stromal cells (MSCs) are widely used in preclinical models of traumatic brain injury (TBI). Results are promising in terms of neurological improvement but are hampered by wide variability in treatm...
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Article
Burden of disease from exposure to secondhand smoke in children in Europe
Secondhand smoke (SHS) exposure at home and fetal SHS exposure during pregnancy are a major cause of disease among children. The aim of this study is quantifying the burden of disease due to SHS exposure in ch...
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Article
Open AccessNational burden of cancer in Italy, 1990–2017: a systematic analysis for the global burden of disease study 2017
We monitored the burden of cancer in Italy and its trends over the last three decades, providing estimates of cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjust...
