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    Article

    The epidermal immune microenvironment plays a dominant role in psoriasis development, as revealed by mass cytometry

    Psoriasis is a common chronic inflammatory skin disease. The diversity and heterogeneity of immune cells in human skin have been studied in recent years, but the spatial distribution of immune cells at the sin...

    Yuan Zhou, Fan Xu, Xue-Yan Chen, Bing-** Yan in Cellular & Molecular Immunology (2022)

  2. Article

    Open Access

    Posterior cruciate ligament reconstruction with independent internal brace reinforcement: surgical technique and clinical outcomes with a minimum two year follow-up

    We developed an augmentation technique for PCL reconstruction with independent internal brace reinforcement and evaluated the functional outcome after PCL reconstruction employing autologous hamstrings augment...

    **n Zhao, Ming Yi Duan, Si Qi Chen, Junyuan Wang, Wenxuan Li in International Orthopaedics (2022)

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    Article

    Cutaneous nerve fibers participate in the progression of psoriasis by linking epidermal keratinocytes and immunocytes

    Recent studies have illustrated that psoriatic lesions are innervated by dense sensory nerve fibers. Psoriatic plaques appeared to improve after central or peripheral nerve injury. Therefore, the nervous syste...

    Si-Qi Chen, Xue-Yan Chen, Ying-Zhe Cui, Bing-** Yan in Cellular and Molecular Life Sciences (2022)

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    Chapter and Conference Paper

    Effective Application of Using a Combination of Wireline Techniques for Well Killing and Tubing Fishing Operations

    Understanding of tubing stuck reason and free point position is critical for successful well killing and fishing operations. Combination of different static and remediation wireline techniques is key for relia...

    Jian-bo Yuan, **n Zheng, Vo Minh, Ying Wang in Proceedings of the International Field Exp… (2021)

  5. Article

    Open Access

    EZH2-inhibitor DZNep enhances apoptosis of renal tubular epithelial cells in presence and absence of cisplatin

    The enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase and induces the trimethylation of histone H3 lysine 27 (H3K27me3) in the promoter of many key genes; EZH2 acts as a transcriptional repress...

    Si-qi Chen, Jia-qi Li, **ao-qiao Wang, Wen-**g Lei, Hao Li, Jiao Wan in Cell Division (2020)

  6. Article

    Open Access

    Decreased brain-expressed X-linked 4 (BEX4) expression promotes growth of oral squamous cell carcinoma

    Brain-expressed X-linked (BEX) 4 is a member of BEX family. The functional role of BEX4 in oral squamous cell carcinoma (OSCC) remains unknown.

    Wei Gao, John Zeng-Hong Li, Si-Qi Chen in Journal of Experimental & Clinical Cancer … (2016)

  7. Article

    Open Access

    A novel cold-adapted type I pullulanase of Paenibacillus polymyxa Nws-pp2: in vivo functional expression and biochemical characterization of glucans hydrolyzates analysis

    Pullulanase is an important debranching enzyme and has been widely utilized to hydrolyse the α-1,6 glucosidic linkages in starch/sugar industry. Selecting new bacterial strains or improving bacterial strains i...

    Wei Wei, **g Ma, Si-Qi Chen, **ang-Hai Cai, Dong-Zhi Wei in BMC Biotechnology (2015)