92 Result(s)

Article

The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with type 2 diabetes mellitus: recent findings from NHANES 2007–2018

This study aims to assess the relationship between NHHR (non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio) and Type 2 diabetes mellitus (T2DM) in US adults, using National...

Mo-Yao Tan, Li Weng, Zhong-Hao Yang, Si-Xuan Zhu, Shan Wu… in Lipids in Health and Disease (2024)

Article

The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3

The anti-foreign tissue (transplant rejection) response, mediated by the immune system, has been the biggest obstacle to successful organ transplantation. There are still many enigmas regarding this process an...

Siyu Zhao, Yunyi Hu, Bicheng Yang, Lichao Zhang, Meiyining Xu… in Cell Death & Disease (2024)

Article

Comprehensive genomic profiling of breast cancers characterizes germline-somatic mutation interactions mediating therapeutic vulnerabilities

Germline-somatic mutation interactions are universal and associated with tumorigenesis, but their role in breast cancer, especially in non-Caucasians, remains poorly characterized. We performed large-scale pro...

Chao Chen, Cai-** Lin, Yu-Chen Pei, Ding Ma, Li Liao, Si-Yuan Li… in Cell Discovery (2023)

Article

Focal ischemic stroke modifies microglia-derived exosomal miRNAs: potential role of mir-212-5p in neuronal protection and functional recovery

Ischemic stroke is a severe type of stroke with high disability and mortality rates. In recent years, microglial exosome-derived miRNAs have been shown to be promising candidates for the treatment of ischemic ...

Si-si Li, Jia-jia Wu, **ang-xin **ng, Yu-lin Li, Jie Ma, Yu-jie Duan… in Biological Research (2023)

Article

Elevated Interleukin-37 Associated with Dengue Viral Load in Patients with Dengue Fever

Dengue remains a public health issue worldwide. Similar to chronic infectious diseases, stimulation of cytokine production is not enough to drive immune effector cells for effective virus clearance. One possib...

Jun-Ai Zhang, Jia-Jun Wang, Wen-Ting Zhang, Li Zhang, Bi-Ying Zheng… in Current Microbiology (2023)

Article

Long-term and effective neutralization against omicron sublineages elicited by four platform COVID-19 vaccines as a booster dose

Yuemiao Zhang, Meng-Ting Luo, Qingqin Wu, Yun-**a Wang, Xupu Ma… in Cell Discovery (2023)

Article

PINK1/Parkin-mediated mitophagy inhibits osteoblast apoptosis induced by advanced oxidation protein products

Osteoblast apoptosis plays an important role in age-related bone loss and osteoporosis. Our previous study revealed that advanced oxidation protein products (AOPPs) could induce nicotinamide adenine dinucleoti...

Wei Li, Wang-Sheng Jiang, Ya-Ru Su, Ke-Wu Tu, Lin Zou… in Cell Death & Disease (2023)

Article

Analysis of Whole Blood and Urine Trace Elements in Children with Autism Spectrum Disorders and Autistic Behaviors

The relationship between trace elements and neurological development is an emerging research focus. We performed a case–control study to explore (1) the differences of 13 trace elements chromium (Cr), manganes...

Gang Zhao, Si-** Liu, **n-yu Gan, Jun-ru Li… in Biological Trace Element Research (2023)

Article

Whole exome sequencing with a focus on cardiac disease-associated genes in families of sudden unexplained deaths in Yunnan, southwest of China

To explore the causes of sudden unexpected death (SUD) and to search for high-risk people, whole exome sequencing (WES) was performed in families with SUDs. 

Si-Jie Wei, **-Liang Du, Yue-Bing Wang, Peng-Fei Qu, Lin Ma… in BMC Genomics (2023)

Article

Single-cell RNA-seq integrated with multi-omics reveals SERPINE2 as a target for metastasis in advanced renal cell carcinoma

Tumor growth, metastasis and therapeutic response are believed to be regulated by the tumor and its microenvironment (TME) in advanced renal cell carcinoma (RCC). However, the mechanisms underlying genomic, tr...

Wen-** Chen, Ke-qin Dong, **u-wu Pan, Si-shun Gan, Da Xu… in Cell Death & Disease (2023)

Article

Restoring mitochondrial cardiolipin homeostasis reduces cell death and promotes recovery after spinal cord injury

Alterations in phospholipids have long been associated with spinal cord injury (SCI). However, their specific roles and signaling cascades in mediating cell death and tissue repair remain unclear. Here we inve...

Nai-Kui Liu, Ling-**ao Deng, Miao Wang, Qing-Bo Lu, Chunyan Wang… in Cell Death & Disease (2022)

Article

OrchidBase 5.0: updates of the orchid genome knowledgebase

Containing the largest number of species, the orchid family provides not only materials for studying plant evolution and environmental adaptation, but economically and culturally important ornamental plants fo...

You-Yi Chen, Chung‐I Li, Yu-Yun Hsiao, Sau-Yee Ho, Zhe-Bin Zhang… in BMC Plant Biology (2022)

Article

Manipulating PP2Acα-ASK-JNK signaling to favor apoptotic over necroptotic hepatocyte fate reduces the extent of necrosis and fibrosis upon acute liver injury

In the widely used Carbon tetrachloride (CCl₄)-induced acute liver injury (ALI) mouse model, hepatocytes are known to die from programmed cell death (PCD) processes including apoptosis and necroptosis. Both in vi...

Ke Lu, Si-Yu Shen, Ou-Yang Luo, Yue Lu, Tian-Shu Shi, **g Wu… in Cell Death & Disease (2022)