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Article
Sodium Metabisulfite: Effects on Ionic Currents and Excitotoxicity
How sodium metabisulfite (SMB; Na2S2O5), a popular food preservative and antioxidant, interacts with excitable membrane and induces excitotoxicity is incompletely understood. In this study, the patch-clamp techni...
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Article
Demonstration of Tightly Radiation-Controlled Molecular Switch Based on CArG Repeats by In Vivo Molecular Imaging
Promoters developed for radiogene therapy always show non-negligible transcriptional activities, even when cells are not irradiated. This study developed a tightly radiation-controlled molecular switch based o...
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Article
Activation and Inhibition of ATM by Phytochemicals: Awakening and Slee** the Guardian Angel Naturally
Double-stranded breaks (DSBs) are cytotoxic DNA lesions caused by oxygen radicals, ionizing radiation, and radiomimetic chemicals. Increasing understanding of DNA damage signaling has provided an ever-expandin...
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Article
Neuroprotective effects of Hu-Yi-Neng, a diet supplement, On SH-SY5Y human neuroblastoma cells
Oxidative stress is considered the potential risk to the development of dementia. Some medicines, vitamins, and diet supplements have been suggested to have possible benefits via the antioxidative effects to s...
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Article
Particle swarm optimization algorithm for analyzing SNP–SNP interaction of renin-angiotensin system genes against hypertension
Most non-significant individual single nucleotide polymorphisms (SNPs) were undiscovered in hypertension association studies. Their possible SNP–SNP interactions were usually ignored and leaded to missing heri...
