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Expression of the NF-κB-responsive gene BTG2 is aberrantly regulated in breast cancer

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  1. Article

    Open Access

    Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade

    Immune checkpoint blockade (ICB) has demonstrated efficacy in patients with melanoma, but many exhibit poor responses. Using single cell RNA sequencing of melanoma patient-derived circulating tumor cells (CTCs...

    Douglas B. Fox, Richard Y. Ebright, **n Hong, Hunter C. Russell… in npj Precision Oncology (2023)

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  2. Article

    Open Access

    Blood-based monitoring identifies acquired and targetable driver HER2 mutations in endocrine-resistant metastatic breast cancer

    Plasma genoty** identifies potentially actionable mutations at variable mutant allele frequencies, often admixed with multiple subclonal variants, highlighting the need for their clinical and functional vali...

    Arielle J. Medford, Taronish D. Dubash, Dejan Juric, Laura Spring… in npj Precision Oncology (2019)

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