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Article
Law of respirable dust pollution induced by cutting-advancing support in a fully mechanized mining face and spatial stereoscopic dust control and removal technology
To reduce the impact of high-concentration RD on the physical and mental health of miners, numerical simulations were conducted on the coupling movement law of airflow-RD under the condition of cutting-advanci...
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Article
Open AccessInfluence of mixed ventilation on particulate-gas diffusion and distribution of diesel engine exhaust in fully mechanized excavation face
Tail gas emitted by underground trackless rubber wheel cars poses a serious threat to the health and safety of underground workers. To effectively reduce the tail gas concentration of a comprehensive excavatio...
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Article
Study on the regional atomized dust suppression technological system based on the measured law of dust concentration distribution in longwall fully mechanized mining faces
In order to reveal the distribution and migration law of downwind and upwind coal cutting, total dust (TD) and respirable dust (RD) concentration distribution and migration on the leeward side of the rear drum...
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Article
Open AccessDexamethasone suppresses immune evasion by inducing GR/STAT3 mediated downregulation of PD-L1 and IDO1 pathways
T cell exhaustion plays critical roles in tumor immune evasion. Novel strategies to suppress immune evasion are in urgent need. We aimed to identify potential compounds to target T cell exhaustion and increase...
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Article
CFD simulation of multi-phase and multi-component diffusion of air-dust-gas in a fully mechanized mining face
To explore the rule of airflow-dust-gas dispersion and interaction in a fully mechanized mining face, the airflow current vector, the dust trajectory, and the gas spatial distribution were numerically simulate...
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Article
Open AccessA positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis
IDO1 (Indoleamine 2,3-dioxygenase 1) inhibits host anti-tumor immune response by exhausting tryptophan in tumor microenvironment, but the pathogenic mechanisms of IDO1 in gastric cancer (GC) cells need to be f...
