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  1. No Access

    Article

    Ligand-enabled palladium-catalysed enantioselective synthesis of α-quaternary amino and glycolic acids derivatives

    α-Quaternary amino and glycolic acids have found application in many biologically relevant compounds and pharmaceuticals. For example, α-quaternary amino acids can act as modifiers of peptide conformation, com...

    Shutao Qi, Wenshao Ye, Yunkai Hua, Liangkai Pan, Junfeng Yang… in Nature Synthesis (2024)

  2. Article

    Open Access

    Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex

    O-GlcNAcylation is a conserved post-translational modification that attaches N-acetyl glucosamine (GlcNAc) to myriad cellular proteins. In response to nutritional and hormonal signals, O-GlcNAcylation regulate...

    ** Lu, Yusong Liu, Maozhou He, Ting Cao, Mengquan Yang… in Nature Communications (2023)

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    Article

    Structural basis of tubulin detyrosination by vasohibins

    Microtubules are regulated by post-translational modifications of tubulin. The ligation and cleavage of the carboxy-terminal tyrosine of α-tubulin impact microtubule functions during mitosis, cardiomyocyte con...

    Faxiang Li, Yingjie Hu, Shutao Qi, Xuelian Luo… in Nature Structural & Molecular Biology (2019)

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    Chapter

    Efficiency of Polar Body Biopsy on Aneuploidy Screening by DNA Microarray for Single Euploid Embryo Transfer

    Aneuploidy is a leading cause of recurrent miscarriage and congenital birth defects. Array-based comparative genomic hybridization (aCGH) can be used to simultaneously examine all 23 pairs of chromosomes in sa...

    Shutao Qi, Ghassan Haddad, Craig Witz, Weihua Wang in Screening the Single Euploid Embryo (2015)