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Seasonal variations in endothelium-dependent flow-mediated vasodilation and endothelium-independent nitroglycerine-induced vasodilation
Cardiovascular mortality has been shown to vary seasonally. However, it has not been determined whether vascular function is affected by the season. The purpose of this study was to investigate the association...
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Open AccessPercentage of mean arterial pressure as a marker of atherosclerosis for detecting patients with coronary artery disease
The percentage of mean arterial pressure (%MAP) is the height of the mean arterial waveform divided by the peak amplitude of the waveform of pulse volume recording. The purpose of this study was to determine w...
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Open AccessAuthor Correction: Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma
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Article
Open AccessGeneration of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma
Organs consist of the parenchyma and stroma, the latter of which coordinates the generation of organotypic structures. Despite recent advances in organoid technology, induction of organ-specific stroma and rec...
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Article
Open AccessImpaired NEPHRIN localization in kidney organoids derived from nephrotic patient iPS cells
Mutations in the NPHS1 gene, which encodes NEPHRIN, cause congenital nephrotic syndrome, resulting from impaired slit diaphragm (SD) formation in glomerular podocytes. We previously reported NEPHRIN and SD abnorm...
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Open AccessReconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation
The kidney possesses a highly organised vasculature that is required for its filtration function. While recent advances in stem cell biology have enabled the in vitro generation of kidney tissues, at least partia...
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Article
Open AccessPAX2 is dispensable for in vitro nephron formation from human induced pluripotent stem cells
The kidney is formed by reciprocal interactions between the nephron progenitor and the ureteric bud, the former of which gives rise to the epithelia of nephrons consisting of glomeruli and renal tubules. The t...
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Article
Open AccessSall1 in renal stromal progenitors non-cell autonomously restricts the excessive expansion of nephron progenitors
The mammalian kidney develops from reciprocal interactions between the metanephric mesenchyme and ureteric bud, the former of which contains nephron progenitors. The third lineage, the stroma, fills up the int...
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Erratum: Stromal–epithelial crosstalk regulates kidney progenitor cell differentiation
Nat. Cell Biol. 15, 1035–1044 (2013); published online 25 August 2013; corrected after print 29 August 2013 In the version of this Article originally published, there was an error in Fig. 4a. The labels “Yap s...
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Stromal–epithelial crosstalk regulates kidney progenitor cell differentiation
Present models suggest that the fate of the kidney epithelial progenitors is solely regulated by signals from the adjacent ureteric bud. The bud provides signals that regulate the survival, renewal and differe...
