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Article
Open AccessCTpathway: a CrossTalk-based pathway enrichment analysis method for cancer research
Pathway enrichment analysis (PEA) is a common method for exploring functions of hundreds of genes and identifying disease-risk pathways. Moreover, different pathways exert their functions through crosstalk. Ho...
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Article
Open AccessncRI: a manually curated database for experimentally validated non-coding RNAs in inflammation
Inflammation has been considered to be central to the onset, progression, and outcome of infectious diseases, especially as one of the hallmarks of cancer. Non-coding RNAs (ncRNAs), such as miRNAs and lncRNAs,...
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Article
Dissecting the m6A methylation affection on afatinib resistance in non-small cell lung cancer
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer deaths. Afatinib is the first-line anti-cancer agent for treatment of NSCLC. However, unexpected resistance has been a major obstacle f...
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Article
Systematical analysis of lncRNA–mRNA competing endogenous RNA network in breast cancer subtypes
Breast cancer is one of the most common solid tumors in women involving multiple subtypes. However, the mechanism for subtypes of breast cancer is still complicated and unclear. Recently, several studies indic...