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Open AccessFasting-mimicking diet remodels gut microbiota and suppresses colorectal cancer progression
The progression of colorectal cancer is closely associated with diet. Fasting-mimicking diet (FMD) is a promising type of dietary intervention that have beneficial effects in the prevention and treatment of va...
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Article
Open AccessMulti-level Factors Associated with HIV Late Presentation with Advanced Disease and Delay Time of Diagnosis in South Carolina, 2005–2019
This study explored individual- and county-level risk factors of late presentation with advanced disease (LPAD) among people with HIV (PWH) and their longer delay time from infection to diagnosis in South Caro...
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Article
Numerical Simulation and Parametric Analysis of Ultrasonic Velocity Test in Fractured Rock Based on the Discrete Element Method
Ultrasonic pulse velocity (UPV) test is widely used to evaluate rock mass integrity. However, it is rather difficult to conduct a sampling of fractured rocks and acquire a set of rocks with different fracture ...
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Article
Open AccessThe dynamic risk factors of cardiovascular disease among people living with HIV: a real-world data study
This study aims to investigate the incidence and dynamic risk factors for cardiovascular diseases (CVD) among people living with HIV (PLWH).
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Article
Open AccessImbalance of gut microbiota in gestational diabetes
To investigate the differences in gut microbiota composition among nonpregnant women of reproductive age, healthy pregnant women, and gestational diabetes (GD) patients.
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Dynamic changes in butyrate levels regulate satellite cell homeostasis by preventing spontaneous activation during aging
The gut microbiota plays a pivotal role in systemic metabolic processes and in particular functions, such as develo** and preserving the skeletal muscle system. However, the interplay between gut microbiota/...
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Correction: COVID-19 Testing Among People with HIV: A Population Level Analysis Based on Statewide Data in South Carolina
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Article
Determining S-Wave Arrival Times for Microseismic Monitoring in Tunnels Based on Instantaneous Phase Difference of Sensors
Accurately ascertaining the S-wave arrival times of microseismic signals is crucial for improving the accuracy with which microseismic events can be located. However, the first arrival of an S-wave is often ov...
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Article
Develo** and testing an integrative model of work-family conflict in a Chinese context
Given that the field of work-family conflict is overwhelmingly Western-focused and that the process of work-family conflict might change under a different cultural background, the aim of the present study was ...
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COVID-19 Testing Among People with HIV: A Population Level Analysis Based on Statewide Data in South Carolina
People with HIV (PWH) are at an elevated risk of develo** severe COVID-19 outcomes because of compromised immunity and more comorbidities. However, existing literature suggests a lower rate of COVID-testing ...
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Article
Exploring the Work-Family Guilt-Conflict Relation: the Role of Time Allocation and Access to Flexibility
Work-family guilt is an under-explored topic in work-family research that requires further investigation, especially considering its antecedent is exclusively focused on work-family conflict and its negative i...
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Article
Open AccessHeat-inactivated Bifidobacterium adolescentis ameliorates colon senescence through Paneth-like-cell-mediated stem cell activation
Declined numbers and weakened functions of intestinal stem cells (ISCs) impair the integrity of the intestinal epithelium during aging. However, the impact of intestinal microbiota on ISCs in this process is u...
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Article
The influence of household size on the experience of work-family conflict
There is a growing need to examine the influence of household size on the experience of work-family conflict, considering the changing family structure worldwide due to the decrease in fertility and mortality ...
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Open AccessCorrection: Bifidobacterium adolescentis induces Decorin+ macrophages via TLR2 to suppress colorectal carcinogenesis
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Open AccessBifidobacterium adolescentis induces Decorin+ macrophages via TLR2 to suppress colorectal carcinogenesis
The interplay between gut microbiota and tumor microenvironment (TME) in the pathogenesis of colorectal cancer (CRC) is largely unknown. Here, we elucidated the functional role of B. adolescentis and its possible...
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An Inverted Heterogeneous Velocity Model for Microseismic Source Location in Deep Buried Tunnels
Microseismic (MS) monitoring is an effective and widely applied technology for early warning and prevention of rockburst disasters in deeply buried tunnels. The location of the microseismic source is the top p...
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Article
An evaluation of aging measures: from biomarkers to clocks
With the increasing number of aged population and growing burden of healthy aging demands, a rational standard for evaluation aging is in urgent need. The advancement of medical testing technology and the pros...
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Numerical study on tunnel damage subject to blast loads in jointed rock masses
Drill and blast method is an accepted technique of tunnel excavation but it often causes over-break or even threatens the stability of the surrounding rock. Moreover, the rock mass mostly contains different fo...
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Open AccessDistribution and characterization of extrachromosomal circular DNA in colorectal cancer
Extrachromosomal circular DNA (eccDNA) has been shown to play an important role in the amplification of tumor genes and the maintenance of intra-tumor genetic heterogeneity, although its complex functional mec...
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Open AccessFusobacterium nucleatum reduces METTL3-mediated m6A modification and contributes to colorectal cancer metastasis
Microbiota-host interactions play critical roles in colorectal cancer (CRC) progression, however, the underlying mechanisms remain elusive. Here, we uncover that Fusobacterium nucleatum (F. nucleatum) induces a d...