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  1. Article

    Open Access

    CDK7/CDK9 mediates transcriptional activation to prime paraptosis in cancer cells

    Paraptosis is a programmed cell death characterized by cytoplasmic vacuolation, which has been explored as an alternative method for cancer treatment and is associated with cancer resistance. However, the mech...

    Shih-Kai Chiang, Wei-Chao Chang, Shuen-Ei Chen, Ling-Chu Chang in Cell & Bioscience (2024)

  2. Article

    Open Access

    Effects of acute heat stress on protein expression and histone modification in the adrenal gland of male layer-type country chickens

    The adrenal gland responds to heat stress by epinephrine and glucocorticoid release to alleviate the adverse effects. This study investigated the effect of acute heat stress on the protein profile and histone ...

    Hao-Teng Zheng, Zi-Xuan Zhuang, Chao-Jung Chen, Hsin-Yi Liao in Scientific Reports (2021)

  3. Article

    Open Access

    Functional genomics study of acute heat stress response in the small yellow follicles of layer-type chickens

    This study investigated global gene and protein expression in the small yellow follicle (SYF; 6–8 mm in diameter) tissues of chickens in response to acute heat stress. Twelve 30-week-old layer-type hens were d...

    Chuen-Yu Cheng, Wei-Lin Tu, Chao-Jung Chen, Hong-Lin Chan in Scientific Reports (2018)

  4. Article

    Open Access

    Docosahexaenoic acid increases accumulation of adipocyte triacylglycerol through up-regulation of lipogenic gene expression in pigs

    Changing dietary fatty acid composition in modern diet influences the prevalence of obesity. Increasing evidences suggest favorable effects of n-3 PUFA for protecting against obesity and the metabolic syndrome...

    Chao-Wei Huang, Yu-Jen Chen, Jui-Ting Yang, Ching-Yi Chen in Lipids in Health and Disease (2017)