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Article
Total ionizing dose effect of gamma rays on H-gate PDSOI MOS devices at different dose rates
The total dose effect of 60Co γ-rays on 0.8-μm H-gate partially depleted-silicon-on-insulator NMOS devices was investigated at different irradiation doses. The results show that the shift in saturation current at...
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Article
Effects of total dose irradiation on the threshold voltage of H-gate SOI NMOS devices
This work researched the impact of total dose irradiation on the threshold voltage of N-type metal oxide semiconductor field effect transistors (nMOSFETs) in silicon-on-insulator (SOI) technology. Using the su...
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Article
Open AccessCD133+ liver cancer stem cells resist interferon-gamma-induced autophagy
Hepatocellular carcinoma (HCC) is one of the most fatal malignancies worldwide, and CD133 is a popular cancer stem cell (CSC) marker for HCC. CD133+ CSCs have been reported to resist conventional chemo- and radio...
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Article
Open AccessMiR-449a suppresses the epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by multiple targets
Increasing evidence indicates that Epithelial–mesenchymal transition (EMT) can be regulated by microRNAs (miRNAs). MiR-449a is a liver abundant miRNA. However, the role of miR-449a in the metastasis of hepatoc...
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Article
Open AccessTransducin β-like 1 X-linked receptor 1 suppresses cisplatin sensitivity in Nasopharyngeal Carcinoma via activation of NF-κB pathway
Transducin β-like 1 X-linked receptor 1 (TBL1XR1) is an important transcriptional cofactor involved in the regulation of many signaling pathways, and is associated with carcinogenesis and tumor progression. Ho...
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Article
Bubble Formation and Heterogeneity of Traders: A Multi-Agent Perspective
Financial bubble is an intensively discussed but quite controversial topic. In current literature, the researches usually focus on the (ir)rationality of traders and its impacts on the bubble. We thereby propo...
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Article
Open AccessAnti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma
Longikaurin A is a natural ent-kaurene diterpenoid isolated from Isodon genus. The ent-kaurene diterpenoids isolated from medicinal plants have been shown to have anti-disease effects. The present study was desig...
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Article
Open AccessAxitinib Targeted Cancer Stemlike Cells to Enhance Efficacy of Chemotherapeutic Drugs via Inhibiting the Drug Transport Function of ABCG2
Stemlike cells have been isolated by their ability to efflux Hoechst 33342 dye and are called the side population (SP). We evaluated the effect of axitinib on targeting cancer stemlike cells and enhancing the ...
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Article
Open AccessDistribution, characterization, and induction of CD8+ regulatory T cells and IL-17-producing CD8+ T cells in nasopharyngeal carcinoma
CD8+ effector cells often have an antitumor function in patients with cancer. However, CD8+Foxp3+ regulatory T cells (Tcregs) and interleukin (IL)-17-producing CD8+ T cells (Tc17 cells) also derive from the CD8+ ...
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Article
Open AccessPrognostic significance and therapeutic implications of centromere protein F expression in human nasopharyngeal carcinoma
Our recent cDNA microarray data showed that centromere protein F (CENP-F) is significantly upregulated in primary cultured nasopharyngeal carcinoma (NPC) tumor cells compared with normal nasopharyngeal epithel...
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Article
Global charm of the Changjiang River Delta
Based on the theory of geo-economy, under the new situation of global economy, information network and China’s entry into WTO, also with the holding of APEC (in 2001) and the International Exposition in the ne...
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Article
The steps forward of GIS in China
Researches and applications of Geographic Information Systems (GIS) in China started in the early 1980s. In the early period, the development of GIS was mainly depended on the progress and applications of remo...