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Article
A New Ester from the Roots of Cannabis sativa
A new amine, 3-methyl-1′-amino-3′-hydroxypropyl pentanoate (1), was isolated from the ethyl acetate extract of the roots of Cannabis sativa L. The structure was established by spectroscopic analyses including 1D ...
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Article
Open AccessDu Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice
Knee osteoarthritis (KOA) has a complex pathological mechanism and is difficult to cure. The traditional medicine Du Huo Ji Sheng Tang (DHJST) has been used for the treatment of KOA for more than one thousand ...
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Article
A New Dihydrochalcone from the Leaves of Malus pumila
A new dihydrochalcone, phloridzin-5′-(1′′,4′′-butyrolactam) (1), was isolated from the ethyl acetate extract of Malus pumila Mill. The structure was established by spectroscopic analyses including 1D and 2D NMR (
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Article
A New Diarylheptanoid from the Barks of Betula platyphylla
A new diarylheptanoid, 3,4-dihydroxy-1,7-bis(4′ ,4′′-dihydroxyphenyl)-heptane (1), was isolated from the ethyl acetate extract of Betula platyphylla. Its structure was established by spectroscopic analyses, inclu...
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Article
A New Lactam from Cannabis sativa
A new lactam, 5-hydroxy-1-[(4-hydroxyphenyl)methyl]-2-pyrrolidinone (1), was isolated from the ethyl acetate extract of Cannabis sativa L. The structure was established by spectroscopic analyses, including 1D and...
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Article
Three New Diterpenoids from the Bark of Ptychopetalum olacoides
A phytochemical constituent investigation of the bark of Ptychopetalum olacoides led to the isolation of three new diterpenoides, named ptycholactone (1), 3(R)-hydroxysarcopetaloic acid (2), and 2β,3β-dihydroxyla...
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Article
Open AccessLocking compression plate distal ulna hook plate fixation versus intramedullary screw fixation for displaced avulsion fifth Metatarsal Base fractures: a comparative retrospective cohort study
Intramedullary screw (IMS) fixation was wildly used in fifth metatarsal base fractures (FMBFs) and the results were satisfactory. However, in the comminuted osteoporosis or small displaced avulsion FMBFs, anat...
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Article
Two New Monoterpenoids from the Fresh Leaves of Syringa oblata
Two new iridoid type monoterpenoids, named syringopicrogenin D (1) and syringopicrogenin E (2), were isolated from the EtOH extract of the fresh leaves of Syringa oblate Lindl. The structures of 1 and 2 were eluc...
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Article
Two New Stachane Diterpenoids from the Bark of Ptychopetalum olacoides
Phytochemical constituents investigation of the bark of Ptychopetalum olacoides led to the isolation of two new stachane diterpenoides, named stach-15-en-12α-ol-3-one (1) and stach-15-en-12β-ol-3-one (2). The str...
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Article
Evidence for Apoplasmic Phloem Unloading in Pear Fruit
Pear is a tree fruit species with worldwide distribution and belongs to the Rosaceae family. In this study, the phloem unloading pathway in pear (Pyrus bretschneideri ‘Yali’) fruit was investigated using transmis...
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Article
Association between melatonin receptor 1A (MTNR1A) gene single-nucleotide polymorphisms and the velvet antler yield of Sika deer
Melatonin, a secretion from pineal gland is ambiguously considered as the key hormone involved in regulation of the antler cycle in Sika deer. To find out more about the roles of melatonin and its receptor gen...
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Article
Investigation of transferability of BovineSNP50 BeadChip from cattle to water buffalo for genome wide association study
Cattle and water buffalo belong to the same subfamily Bovinae and share chromosome banding and gene order homology. In this study, we used genome-wide Illumina BovineSNP50 BeadChip to analyze 91 DNA samples from ...
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Article
Polymorphisms in luteinizing hormone receptor and hypothalamic gonadotropin-releasing hormone genes and their effects on sperm quality traits in Chinese Holstein bulls
Genes of hypothalamic-pituitary–gonadal axis play a key role in male reproductive performance. This study evaluated the polymorphisms of luteinizing hormone receptor (LHR) and hypothalamic gonadotropin-releasi...
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Article
Molecular analysis of eight SFB alleles and a new SFB-like gene in Prunus pseudocerasus and Prunus speciosa
This study identified eight S-haplotype-specific F-box genes (SFB alleles) and one S-haplotype-specific F-box-like gene (SFB-like gene) from genomic DNA by PCR combined with cleaved amplified polymorphic sequence...
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Article
Open AccessFresh raspberry phytochemical extract inhibits hepatic lesion in a Wistar rat model
Red raspberry possesses potent antioxidant capacity and antiproliferative activity against cancer in vitro.
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Article
Open AccessDifferential expression of proteomics models of colorectal cancer, colorectal benign disease and healthy controls
Colorectal cancer (CRC) is often diagnosed at a late stage with concomitant poor prognosis. The hypersensitive analytical technique of proteomics can detect molecular changes before the tumor is palpable. The ...
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Article
An Innovative Methodology of Product Design from Nature
Nature is an information sourcebook of behaviour, function, colour and shape which can inspire visual design and invention. Studying the form and functional characteristics of a natural object can provide insp...
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Article
Optimising body layout design of limbed machines
This paper presents our efforts to explain why mammals have large thigh muscles while insects have small ones. After a discussion of this observation a definition of body foot ratio is defined which describes ...
