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  1. No Access

    Article

    MiR-449a downregulation alleviates the progression of renal interstitial fibrosis by mediating the KLF4/MFN2 axis

    Renal interstitial fibrosis (RIF) seriously threatens the health of individuals. MiRNAs regulate the progression of fibrosis. Nevertheless, the detailed function of miR-449a in RIF is largely unknown.

    **ang-Dong Fang, Jia-Ke He, Yan-**a Chen, Ben Ke… in International Urology and Nephrology (2023)

  2. No Access

    Article

    Overexpression of HOTAIR attenuates Pi-induced vascular calcification by inhibiting Wnt/β-catenin through regulating miR-126/Klotho/SIRT1 axis

    Vascular calcification is one of the most common effects of macrovascular complications in patients in aging with chronic kidney disease and diabetes. Previous studies showed that HOTAIR attenuated vascular c...

    Yan Chen, Chong Huang, Shu-Ying Zhu, Hong-Chang Zou… in Molecular and Cellular Biochemistry (2021)

  3. No Access

    Article

    Select aging biomarkers based on telomere length and chronological age to build a biological age equation

    The purpose of this study is to build a biological age (BA) equation combining telomere length with chronological age (CA) and associated aging biomarkers. In total, 139 healthy volunteers were recruited from ...

    Wei-Guang Zhang, Shu-Ying Zhu, **ao-Juan Bai, De-Long Zhao, Shi-Min Jiang, Juan Li… in AGE (2014)

  4. No Access

    Article

    A Novel PrP Partner HS-1 Associated Protein X-1 (HAX-1) Protected the Cultured Cells Against the Challenge of H2O2

    Prion protein (PrP) is a ubiquitous conserved glycoprotein predominantly expressed in neurons of the central nervous system (CNS). To elucidate on its cellular function, we performed a yeast two-hybrid screen ...

    Yuan-Yuan **g, **ao-Li Li, Qi Shi, Zhao-Yun Wang… in Journal of Molecular Neuroscience (2011)