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Article
Finite-temperature ductility-brittleness and electronic structures of AlnSc (n = 1, 2 and 3)
Finite-temperature ductility-brittleness and electronic structures of Al3Sc, Al2Sc and AlSc are studied comparatively by first-principles calculations and ab initio molecular dynamics. Results show that Al3Sc and...
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Article
Cross-linked Sodium Hyaluronate Gel with PLLA-b-PEG Microsphere for Facial Contouring in Chinese: A Retrospective Study
In Asia, the demand for cosmetic facial treatments has surged due to technological advancements, increased social acceptability, and affordability. Poly-l-lactic acid (PLLA) fillers, known for their biocompatibil...
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Article
Machine Learning Approach in Dosage Individualization of Isoniazid for Tuberculosis
Isoniazid is a first-line antituberculosis agent with high variability, which would profit from individualized dosing. Concentrations of isoniazid at 2 h (C2h), as an indicator of safety and efficacy, are importa...
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Article
Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic acid cycle and subsequent loss of iron-sulfur cluster proteins as a unique copper-dependent form of regulated cell dea...
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Article
Evolution of Inclusion Distribution in Continuous Casting Slabs During Strip Feeding
Feeding strip significantly enhances continuous cast slab quality. To clarify its impact on inclusion distribution, a mathematical model coupling flow, solidification and inclusion motion have been developed. ...
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Article
A Mn-porphyrinic metal–organic framework immobilizing glucose oxidase for combined photodynamic/chemodynamic/starvation therapy
The combination of photodynamic therapy (PDT) and chemodynamic therapy (CDT) in tumor treatment has attracted considerable attention. However, tumor hypoxia and glutathione (GSH) overproduction in the tumor ti...
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Article
Open AccessDesigning Symmetric Gradient Honeycomb Structures with Carbon-Coated Iron-Based Composites for High-Efficiency Microwave Absorption
MIL-88C (Fe) with varying aspect ratios as a precursor was synthesized by regulating oil bath conditions, followed by one-step thermal decomposition to obtain carbon-coated iro...
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Article
Crenobacter oryzisoli sp. nov., a novel phosphate-solubilizing bacterium isolated from the paddy soil
Two Gram-staining-negative, facultative anaerobic, rod-shaped and phosphate-solubilizing strains designated SG2303T and SG2305, were isolated from paddy soil in China. Phylogenetic analysis based on 16 S rRNA gen...
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Article
Biosafety assessments of hexafluoropropylene trimer derivative as a fluorinated cooling fluid for electronics
The Internet Data Center (IDC) is one of the most important infrastructures in the field of information technology. The cooling system for heat dissipation of IDC is indispensable due to it generates a large a...
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Article
Cleanliness Improvement and Microstructure Refinement of As-Cast High-Nitrogen Stainless Bearing Steel by Magnesium Treatment
The influence of magnesium treatment on cleanliness and microstructure characteristics of as-cast high-nitrogen stainless bearing steel (HNSBS) was systematically investigated. Results manifested that as the m...
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Article
Open AccessCorrection: Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease
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Article
Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability
The impairment of blood-brain barrier (BBB) integrity is the pathological basis of hemorrhage transformation and vasogenic edema following thrombolysis and endovascular therapy. There is no approved drug in th...
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Article
Elucidating the Influence Mechanism of Vanadium Addition on Dendritic Structure and Precipitated Phase of 30Cr15Mo1N Ingot During Pressurized Solidification
By analyzing element segregation and dendritic growth kinetics in combination with microstructure observation and thermodynamic calculation, the influence mechanism of vanadium addition on the dendritic struct...
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Article
Optimal ternary locally repairable codes
Locally repairable codes (LRCs) are linear codes with locality properties for code symbols, which have important applications in distributed storage systems. In this paper, we completely classify all the possi...
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Article
Property evolution and service life prediction of novel metallic materials for future lunar bases
While lunar bases have been a focus of development in recent years, the complex and extreme environment of the lunar surface remains a considerable challenge for lunar exploration. Unlike those on Earth, lunar...
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Article
Contrasting strategies of optimizing carrier concentration in bulk InSe for enhanced thermoelectric performance
Indium selenide (InSe), as a wide-bandgap semiconductor, has received extensive attention in the flexible electronics field in recent years due to its exceptional plasticity and promising thermoelectric perfor...
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Article
Open AccessAssociation between pretreatment emotional distress and immune checkpoint inhibitor response in non-small-cell lung cancer
Emotional distress (ED), commonly characterized by symptoms of depression and/or anxiety, is prevalent in patients with cancer. Preclinical studies suggest that ED can impair antitumor immune responses, but fe...
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Article
Crosstalk among Oxidative Stress, Autophagy, and Apoptosis in the Protective Effects of Ginsenoside Rb1 on Brain Microvascular Endothelial Cells: A Mixed Computational and Experimental Study
Brain microvascular endothelial cells (BMECs) were found to shift from their usually inactive state to an active state in ischemic stroke (IS) and cause neuronal damage. Ginsenoside Rb1 (GRb1), a component der...
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Article
Characteristics and Risk Factors for Pediatric Sepsis
Sepsis is considered a major cause of health loss in children and had high mortality and morbidity. Currently, there is no reliable model for predicting the prognosis of pediatric patients with sepsis. This st...
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Article
Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells
Telomere repeat binding factor 2 (TRF2), a critical element of the shelterin complex, plays a vital role in the maintenance of genome integrity. TRF2 overexpression is found in a wide range of malignant cancer...
