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  1. No Access

    Article

    Changes in skeletal muscle function during chemotherapy and related factors in patients with acute leukemia

    Skeletal muscle function is an important prognostically relevant indicator in patients with acute leukemia (AL), but skeletal dysfunction during chemotherapy is not well understood. This study aimed to investi...

    Yusuke Terao, Yasuhide Nakayama, Masahiro Abo, Yuhei Otobe in Supportive Care in Cancer (2024)

  2. Article

    Open Access

    Development of optimization method for truss structure by quantum annealing

    In this study, we developed a new method of topology optimization for truss structures by quantum annealing. To perform quantum annealing analysis with real variables, representation of real numbers as a sum o...

    Rio Honda, Katsuhiro Endo, Taichi Kaji, Yudai Suzuki, Yoshiki Matsuda in Scientific Reports (2024)

  3. Article

    Gender-specific Characteristics of Social Factors Related to Frequency of Daily Conversation Among Community-dwelling Older Adults: A Cross-sectional Observational Study

    This study examined the social factors affecting the frequency of going out, and social isolation related to the frequency of daily conversation, stratified by gender.

    Mizue Suzuki, Yuhei Otobe, Takeo Ichikawa, Shingo Koyama in Ageing International (2023)

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    Article

    What is the optimal nutritional assessment tool for predicting decline in the activity of daily living among older patients with heart failure?

    The clinical importance of nutritional management in activities of daily living (ADL) among older inpatients with heart failure (HF) is greatly increasing. We determined the optimal nutritional assessment tool...

    Iwao Kojima, Shu Tanaka, Yuhei Otobe, Mizue Suzuki, Shingo Koyama in Heart and Vessels (2022)

  5. Article

    Open Access

    Genetic analysis of Japanese patients with small bowel adenocarcinoma using next-generation sequencing

    Small bowel adenocarcinomas (SBAs) are rare and there is little comprehensive data on SBA genomic alterations for Asian patients. This study aimed to profile genomic alterations of SBA in Japanese patients usi...

    Atsushi Tatsuguchi, Takeshi Yamada, Koji Ueda, Hiroyasu Furuki in BMC Cancer (2022)

  6. Article

    Open Access

    A phase-field model by an Ising machine and its application to the phase-separation structure of a diblock polymer

    A novel model to be applied to next-generation accelerators, Ising machines, is formulated on the basis of the phase-field model of the phase-separation structure of a diblock polymer. Recently, Ising machines...

    Katsuhiro Endo, Yoshiki Matsuda, Shu Tanaka, Mayu Muramatsu in Scientific Reports (2022)

  7. Article

    Open Access

    Two isoforms of TALDO1 generated by alternative translational initiation show differential nucleocytoplasmic distribution to regulate the global metabolic network

    Transaldolase 1 (TALDO1) is a rate-limiting enzyme involved in the pentose phosphate pathway, which is traditionally thought to occur in the cytoplasm. In this study, we found that the gene TALDO1 has two transla...

    Tetsuji Moriyama, Shu Tanaka, Yasumune Nakayama, Masahiro Fukumoto in Scientific Reports (2016)

  8. Article

    Open Access

    Double-twist cylinders in liquid crystalline cholesteric blue phases observed by transmission electron microscopy

    Cholesteric blue phases are liquid crystalline phases in which the constituent rod-like molecules spontaneously form three-dimensional, helical structures. Despite theoretical predictions that they are compose...

    Shu Tanaka, Hiroyuki Yoshida, Yuto Kawata, Ryusuke Kuwahara in Scientific Reports (2015)

  9. Article

    Open Access

    Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancer

    The ErbB family consists of four proteins including (EGFR)/ErbB1, ErbB2, ErbB3, and ErbB4, and plays a crucial role in the promotion of multiple tumorigenic processes. In addition to the traditional pathways o...

    Keigo Mitsui, Masaoki Yonezawa, Atsushi Tatsuguchi, Seiichi Shinji in BMC Cancer (2014)

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    Article

    A case of IgG4-related disease with rectal cancer

    A 72-year-old male with liver dysfunction and an increase in serum total protein/albumin (TP/Alb) ratio was referred to our hospital. There was a marked increase in serum immunoglobulin (Ig) G4 level (IgG/IgG4...

    Norio Itokawa, Masanori Atsukawa, Takayoshi Nishino in Clinical Journal of Gastroenterology (2011)

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    Article

    Rebamipide has the potential to reduce the intensity of NSAID-induced small intestinal injury: a double-blind, randomized, controlled trial evaluated by capsule endoscopy

    A study reported that rebamipide was effective at reducing short-term nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy. The purpose of this study was to re-evaluate the effect of the co-administ...

    Shunji Fujimori, Yoko Takahashi, Katya Gudis, Tsuguhiko Seo in Journal of Gastroenterology (2011)

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    Article

    Microsomal prostaglandin E synthase protein levels correlate with prognosis in colorectal cancer patients

    The aim of this study is to investigate the expression of three prostaglandin E synthase (PGES) isomers in colorectal cancer (CRC) tissue and to evaluate their relationship to clinicopathological factors and p...

    Tsuguhiko Seo, Atsushi Tatsuguchi, Seiichi Shinji, Masaoki Yonezawa in Virchows Archiv (2009)