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  1. Article

    Open Access

    Global map** of live cell mechanical features using PeakForce QNM AFM

    Atomic force microscopy (AFM) has been widely used to acquire surface topography upon different scanning modes and to quantify mechanical properties of a cell using single-point ramp force mode. However, these...

    **rong Hu, Shenbao Chen, Dandan Huang, Yan Zhang, Shouqin Lü in Biophysics Reports (2020)

  2. No Access

    Article

    Mechanochemical modeling of neutrophil migration based on four signaling layers, integrin dynamics, and substrate stiffness

    Directional neutrophil migration during human immune responses is a highly coordinated process regulated by both biochemical and biomechanical environments. In this paper, we developed an integrative mathemati...

    Shiliang Feng, Lüwen Zhou, Yan Zhang in Biomechanics and Modeling in Mechanobiology (2018)

  3. No Access

    Article

    Theoretical modeling of mechanical homeostasis of a mammalian cell under gravity-directed vector

    Translocation of dense nucleus along gravity vector initiates mechanical remodeling of a eukaryotic cell. In our previous experiments, we quantified the impact of gravity vector on cell remodeling by placing a...

    Lüwen Zhou, Chen Zhang, Fan Zhang in Biomechanics and Modeling in Mechanobiology (2018)

  4. No Access

    Chapter and Conference Paper

    Distinct Kinetics Features of LFA-1 and Mac-1 in Neutrophil Activation

    LFA-1 and Mac-1, two β 2 integrin members constitutively expressed on neutrophils, mediate leukocyte recruitment cascade by binding to the same ligand of ICAM-1. The slow rolling and firm adhesion o...

    Ning Li, Debin Mao, Yixin Gong, Shouqin Lü in World Congress on Medical Physics and Biom… (2013)