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  1. Article

    Open Access

    Identification of the Conformational transition pathway in PIP2 Opening Kir Channels

    The gating of Kir channels depends critically on phosphatidylinositol 4,5-bisphosphate (PIP2), but the detailed mechanism by which PIP2 regulates Kir channels remains obscure. Here, we performed a series of Targe...

    Junwei Li, Shouqin Lü, Yuzhi Liu, Chunli Pang, Yafei Chen in Scientific Reports (2015)

  2. No Access

    Article

    Forced extension of P-selectin construct using steered molecular dynamics

    P-selectin, a 70-nm-long cellular adhesive molecule, possesses elastic and extensible properties when neutrophils roll over the activated endotheliam of blood vessel in inflammatory reaction. Transient formati...

    Shouqin Lü, Long Mian in Chinese Science Bulletin (2004)