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Article
Open AccessSingle molecular investigation of DNA loo** and aggregation by restriction endonuclease BspMI
DNA loo** and aggregation induced by restriction endonuclease BspMI are studied by atomic force microscopy (AFM) and magnetic tweezers (MT). With Ca2+ substituted for the normal enzyme cofactor Mg2+ and enzyme ...
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Article
Single molecule DNA compaction by purified histones
The compaction of single DNA molecules by purified histones is studied using magnetic tweezers. The compaction rate increases rapidly when the histone concentration is increased from 0.002 to 0.2 mmol/L, and s...