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    Article

    The infant gut virome is associated with preschool asthma risk independently of bacteria

    Bacteriophage (also known as phage) communities that inhabit the gut have a major effect on the structure and functioning of bacterial populations, but their roles and association with health and disease in ea...

    Cristina Leal Rodríguez, Shiraz A. Shah, Morten Arendt Rasmussen in Nature Medicine (2024)

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    Open Access

    Expanding known viral diversity in the healthy infant gut

    The gut microbiome is shaped through infancy and impacts the maturation of the immune system, thus protecting against chronic disease later in life. Phages, or viruses that infect bacteria, modulate bacterial ...

    Shiraz A. Shah, Ling Deng, Jonathan Thorsen, Anders G. Pedersen in Nature Microbiology (2023)

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    Article

    Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants

    The number and diversity of known CRISPR–Cas systems have substantially increased in recent years. Here, we provide an updated evolutionary classification of CRISPR–Cas systems and cas genes, with an emphasis on ...

    Kira S. Makarova, Yuri I. Wolf, Jaime Iranzo in Nature Reviews Microbiology (2020)

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    Article

    An updated evolutionary classification of CRISPR–Cas systems

  5. CRISPR–Cas systems provide archaea and bacteria with adaptive immunity against viruses and plasmids.

  6. CRISPR...

  7. Kira S. Makarova, Yuri I. Wolf, Omer S. Alkhnbashi in Nature Reviews Microbiology (2015)