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  1. No Access

    Protocol

    Lactoferricin-Derived L5a Cell-Penetrating Peptide for Delivery of DNA into Cells

    Cell-penetrating peptides (CPPs) are small peptides which help intracellular delivery of functional macromolecules, including DNAs, RNAs, and proteins, across the cell membrane and into the cytosol, and even i...

    Natalie J. Holl, Moumita Dey, Yue-Wern Huang, Shiow-Her Chiou in Bio-Carrier Vectors (2021)

  2. Article

    Open Access

    Polyhistidine facilitates direct membrane translocation of cell-penetrating peptides into cells

    The bovine lactoferricin L6 (RRWQWR) has been previously identified as a novel cell-penetrating peptide (CPP) that is able to efficiently internalize into human cells. L6 interacts with quantum dots (QDs) nonc...

    Han-Jung Lee, Yue-Wern Huang, Shiow-Her Chiou, Robert S. Aronstam in Scientific Reports (2019)

  3. Article

    Open Access

    The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells

    Epithelial-to-mesenchymal transition (EMT) has, in recent years, emerged as an important tumor cell behavior associated with high metastatic potential and drug resistance. Interestingly, protein SUMOylation an...

    Nithila A. Joseph, Shiow-Her Chiou, Zoe Lung in Journal of Hematology & Oncology (2018)

  4. Article

    Open Access

    Association of anticardiolipin, antiphosphatidylserine, anti-β2 glycoprotein I, and antiphosphatidylcholine autoantibodies with canine immune thrombocytopenia

    In humans, the presence of antiphospholipid antibodies (aPL) is frequently found in immune thrombocytopenia. The present study investigated whether aPL and any aPL subtypes are associated with canine thrombocy...

    Yu-Chen Chen, Lang-Ming Chi, Kuan-Chih Chow, Shiow-Her Chiou in BMC Veterinary Research (2016)

  5. No Access

    Article

    Downregulated CXCL12 expression in mesenchymal stem cells associated with severe aplastic anemia in children

    The mechanisms of idiopathic severe aplastic anemia (SAA) in children are not completely understood. Insufficiency of the bone marrow microenvironment, in which mesenchymal stem cells (MSCs) are an important e...

    Yu-Hua Chao, Kang-Hsi Wu, Shiow-Her Chiou, Shu-Fen Chiang in Annals of Hematology (2015)

  6. No Access

    Article

    Species Diversity and Substrate Utilization Patterns of Thermophilic Bacterial Communities in Hot Aerobic Poultry and Cattle Manure Composts

    This study investigated the species diversity and substrate utilization patterns of culturable thermophilic bacterial communities in hot aerobic poultry and cattle manure composts by coupling 16S rDNA analysis...

    Chao-Min Wang, Ching-Lin Shyu, Shu-Peng Ho, Shiow-Her Chiou in Microbial Ecology (2007)