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  1. Article

    Open Access

    Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation

    Lung mast cells are important in host defense, and excessive proliferation or activation of these cells can cause chronic inflammatory disorders like asthma. Two parallel pathways induced by KIT–stem cell fact...

    Youn Jung Choi, Ji-Seung Yoo, Kyle Jung, Logan Rice, Dokyun Kim in Nature Communications (2023)

  2. Article

    Open Access

    OASL phase condensation induces amyloid-like fibrillation of RIPK3 to promote virus-induced necroptosis

    RIPK3–ZBP1–MLKL-mediated necroptosis is a proinflammatory cell death process that is crucial for antiviral host defence. RIPK3 self-oligomerization and autophosphorylation are prerequisites for executing necro...

    Shin-Ae Lee, Lin-Chun Chang, WooRam Jung, James W. Bowman in Nature Cell Biology (2023)

  3. Article

    Open Access

    Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferrets

    While the seroprevalence of SARS-CoV-2 in healthy people does not differ significantly among age groups, those aged 65 years or older exhibit strikingly higher COVID-19 mortality compared to younger individual...

    Young-Il Kim, Kwang-Min Yu, June-Young Koh, Eun-Ha Kim, Se-Mi Kim in Nature Communications (2022)

  4. No Access

    Article

    Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses

    The most frequent fetal birth defect associated with prenatal Zika virus (ZIKV) infection is brain calcification, which in turn may potentially affect neurological development in infants. Understanding the mec...

    Weiqiang Chen, Suan-Sin Foo, Eun** Hong, Christine Wu, Wai-Suet Lee in Nature Microbiology (2021)

  5. No Access

    Article

    Chitinophaga agri sp. nov., a bacterium isolated from soil of reclaimed land

    A Gram-negative, aerobic, and long rod-shaped bacterium, designated as H33E-04T, was isolated from the soil of reclaimed land, Republic of Korea. The strain grew at a temperature range of 15–40 °C, pH 5.0–10.0, a...

    Shin Ae Lee, Jun Heo, Tae-Wan Kim, Mee-Kyung Sang in Archives of Microbiology (2021)

  6. No Access

    Article

    Xylophilus rhododendri sp. nov., Isolated from Flower of Royal Azalea, Rhododendron schlippenbachii

    A bacterial strain, designated CJ1-R5T, was isolated from the flower of the royal azalea plant (Rhododendron schlippenbachii) collected in Jeju Island, Republic of Korea. The strain was a Gram-negative, strictly ...

    Shin Ae Lee, Jun Heo, Tae-Wan Kim, Mee-Kyung Sang, Jaekyeong Song in Current Microbiology (2020)

  7. Article

    Open Access

    Different types of agricultural land use drive distinct soil bacterial communities

    Biogeographic patterns in soil bacterial communities and their responses to environmental variables are well established, yet little is known about how different types of agricultural land use affect bacterial...

    Shin Ae Lee, Jeong Myeong Kim, Yiseul Kim, Jae-Ho Joa, Seong-Soo Kang in Scientific Reports (2020)

  8. No Access

    Article

    Paenibacillus lycopersici sp. nov. and Paenibacillus rhizovicinus sp. nov., isolated from the rhizosphere of tomato (Solanum lycopersicum)

    Two Gram-stain-positive, rod-shaped, endospore-forming bacteria, designated 12200R-189T and 14171R-81T were isolated from the rhizosphere of tomato plants. The 16S rRNA gene sequence similarity between strains 12...

    Shin Ae Lee, Tae-Wan Kim, Jun Heo, Mee-Kyung Sang in Journal of Microbiology (2020)

  9. Article

    Open Access

    A preliminary examination of bacterial, archaeal, and fungal communities inhabiting different rhizocompartments of tomato plants under real-world environments

    Plant microbiota is a key determinant of plant health and productivity. The composition and structure of plant microbiota varies according to plant tissue and compartment, which are specific habitats for micro...

    Shin Ae Lee, Yiseul Kim, Jeong Myeong Kim, Bora Chu, Jae-Ho Joa in Scientific Reports (2019)

  10. No Access

    Article

    Chryseolinea soli sp. nov., isolated from soil

    A yellow-colored bacterium with gliding motility, strain KIS68-18T, was isolated from a soil sample at Bi** Island in Tongyeong city, Republic of Korea. The cells were strictly aerobic, Gram-staining-negative, n...

    Shin Ae Lee, Yiseul Kim, Mee-Kyung Sang, Jaekyeong Song in Journal of Microbiology (2019)

  11. No Access

    Article

    Characterization of the GRAS transcription factor SCARECROW-LIKE 28’s role in Arabidopsis root growth

    The roles of multiple GRAS transcription factors (TFs), which play key roles in diverse processes of growth and development, have been characterized in detail. However, the regulatory functions of one third of...

    Jeong-eun Choe, Bohye Kim, Eun Kyung Yoon, Sejeong Jang in Journal of Plant Biology (2017)

  12. No Access

    Article

    Effects of diet type, developmental stage, and gut compartment in the gut bacterial communities of two Cerambycidae species (Coleoptera)

    The gut bacterial community of wood-feeding beetles has been examined for its role on plant digestion and biocontrol method development. Monochamus alternatus and Psacothea hilaris, both belonging to the subfamil...

    Jeong Myeong Kim, Min-Young Choi, Jae-Woo Kim, Shin Ae Lee in Journal of Microbiology (2017)

  13. No Access

    Article

    Comparative analysis of bacterial diversity in the rhizosphere of tomato by culture-dependent and -independent approaches

    The microbiome in the rhizosphere–the region surrounding plant roots–plays a key role in plant growth and health, enhancing nutrient availability and protecting plants from biotic and abiotic stresses. To asse...

    Shin Ae Lee, Jiyoung Park, Bora Chu, Jeong Myeong Kim in Journal of Microbiology (2016)

  14. No Access

    Article

    Soil pH and electrical conductivity are key edaphic factors sha** bacterial communities of greenhouse soils in Korea

    Soil microorganisms play an essential role in soil ecosystem processes such as organic matter decomposition, nutrient cycling, and plant nutrient availability. The land use for greenhouse cultivation has been ...

    Jeong Myeong Kim, An-Sung Roh, Seung-Chul Choi, Eun-Jeong Kim in Journal of Microbiology (2016)

  15. No Access

    Article

    Siphonobacter intestinalis sp. nov., a bacterium isolated from the feces of Pseudorhynchus japonicus

    Strain 63MJ-2T was isolated from the feces of broad-winged katydid (Pseudorhynchus japonicus) collected in Korea. The 16S rRNA gene sequence of this strain showed the highest sequence similarity with that of Siph...

    Shin Ae Lee, Jeong Myeong Kim, Jae-Hyung Ahn, Jae-Ho Joa in Journal of Microbiology (2016)

  16. No Access

    Article

    Dynamics of bacterial communities in rice field soils as affected by different long-term fertilization practices

    Fertilization and the response of the soil microbial community to the process significantly affect crop yield and the environment. In this study, the seasonal variation in the bacterial communities in rice fie...

    Jae-Hyung Ahn, Shin Ae Lee, Jeong Myeong Kim, Myung-Sook Kim in Journal of Microbiology (2016)

  17. No Access

    Article

    Characterization of SHORT-ROOT function in the Arabidopsis root vascular system

    Development of the vascular tissues is a dynamic process that integrates extrinsic and intrinsic factors to control vascular tissue formation throughout the plant life cycle. During vascular tissue formation in A...

    Nan-Ie Yu, Shin Ae Lee, Mi-Hyun Lee, Jung-Ok Heo, Kwang Suk Chang in Molecules and Cells (2010)

  18. No Access

    Article

    Expression of VEGF, EGFR, and IL-6 in Gastric Adenomas and Adenocarcinomas by Endoscopic Submucosal Dissection

    The degree of intratumoral microvascular density is thought to affect tumor metastasis and prognosis in various human cancers, including gastric cancer. Despite recent medical advancements, gastric adenoma or ...

    Shin-Ae Lee, Seok-Reyol Choi, **-Seok Jang in Digestive Diseases and Sciences (2010)

  19. No Access

    Article

    Overexpression and Inactivation of UGT73B2 Modulate Tolerance to Oxidative Stress in Arabidopsis

    Glycosyltransferases (GTs) play an important role in modulating solubility, stability, bioavailability, and bioactivity of secondary metabolites, such as flavonoids. In Arabidopsis thaliana, at least 120 family 1...

    In A Kim, Jung-Ok Heo, Kwang Suk Chang, Shin Ae Lee in Journal of Plant Biology (2010)

  20. No Access

    Article

    Large-scale analysis of the GRAS gene family in Arabidopsis thaliana

    GRAS proteins belong to a plant-specific transcription factor family. Currently, 33 GRAS members including a putative expressed pseudogene have been identified in the Arabidopsis genome. With a reverse genetic ap...

    Mi-Hyun Lee, Bohye Kim, Sang-Kee Song, Jung-Ok Heo, Nan-Ie Yu in Plant Molecular Biology (2008)