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  1. No Access

    Article

    Thick mesopancreas is a novel predictor of surgical outcomes of patients who undergo pancreaticoduodenectomy

    Mesopancreas resection is a crucial but difficult procedure when performing pancreaticoduodenectomy. This study evaluated the influence of mesopancreas thickness on surgical outcomes in patients undergoing pan...

    Yuhei Endo, Hiroshi Noda, Masahiro Iseki in Langenbeck's Archives of Surgery (2024)

  2. Article

    Open Access

    Disease-related protein co-expression networks are associated with the prognosis of resectable node-positive pancreatic ductal adenocarcinoma

    Pancreatic ductal adenocarcinoma (PDAC) is a multifactorial disease, the molecular profile of which remains unclear. This study aimed at unveiling the disease-related protein networks associated with different...

    Toshihide Nishimura, Tatsuyuki Takadate, Shimpei Maeda in Scientific Reports (2022)

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    Article

    Prognostic value of an inflammation-based nutritional score for patients with initially unresectable pancreatic adenocarcinoma undergoing conversion surgery following chemo-/radiotherapy

    To clarify the prognostic value of the preoperative nutrition status of patients undergoing conversion surgery (CS) for initially unresectable pancreatic adenocarcinoma (UR-PA).

    Takashi Kokumai, Shuichi Aoki, Masamichi Mizuma, Shimpei Maeda in Surgery Today (2021)

  4. Article

    Open Access

    Probiotic-related bacteremia after major hepatectomy for biliary cancer: a report of two cases

    Probiotics have been reported to be beneficial for the prevention of postoperative complications and are often used during the perioperative period. Among the probiotic-related adverse events, bacteremia is ra...

    Mitsuhiro Shimura, Masamichi Mizuma, Kei Nakagawa, Shuichi Aoki in Surgical Case Reports (2021)

  5. No Access

    Article

    Staging laparoscopy is mandatory for the treatment of pancreatic cancer to avoid missing radiologically negative metastases

    Staging laparoscopy is considered useful for determining treatment plans for advanced pancreatic cancer. However, the indications for staging laparoscopy are not clear. This study aimed to evaluate the safety ...

    Tatsuyuki Takadate, Takanori Morikawa, Masaharu Ishida, Shuichi Aoki in Surgery Today (2021)

  6. Article

    Open Access

    Increased neutrophil–lymphocyte ratio predicts recurrence in patients with well-differentiated pancreatic neuroendocrine neoplasm based on the 2017 World Health Organization classification

    The prognostic values of inflammation-based markers in well-differentiated pancreatic neuroendocrine neoplasms, diagnosed according to the new 2017 World Health Organization classification, have remained uncle...

    Takayuki Miura, Hideo Ohtsuka, Takeshi Aoki, Shuichi Aoki, Tatsuo Hata in BMC Surgery (2021)

  7. Article

    Open Access

    Novel candidate factors predicting the effect of S-1 adjuvant chemotherapy of pancreatic cancer

    The collagen gel droplet-embedded drug sensitivity test (CD-DST) was revealed to be useful for predicting the effect of S-1 adjuvant chemotherapy for pancreatic ductal adenocarcinoma (PDAC). However, collectio...

    Katsutaka Mitachi, Kyohei Ariake, Hiroki Shima, Satoko Sato in Scientific Reports (2021)

  8. No Access

    Article

    Prognostic indicators in pancreatic cancer patients undergoing total pancreatectomy

    To evaluate the long-term outcomes of total pancreatectomy in a modern cohort of pancreatic cancer patients and to establish whether any factors identified prior to pancreatic resection were related to poor su...

    Shimpei Maeda, Kyohei Ariake, Masahiro Iseki, Hideo Ohtsuka in Surgery Today (2020)

  9. Article

    Open Access

    Novel biomarkers distinguishing pancreatic head Cancer from distal cholangiocarcinoma based on proteomic analysis

    The differentiation between pancreatic head cancer (PHC) and distal cholangiocarcinoma (DCC) can be challenging because of their anatomical and histopathological similarity. This is an important problem, becau...

    Tsutomu Takenami, Shimpei Maeda, Hideaki Karasawa, Takashi Suzuki in BMC Cancer (2019)

  10. No Access

    Article

    18-Fluorodeoxyglucose Positron Emission Tomography Predicts Recurrence in Resected Pancreatic Ductal Adenocarcinoma

    We aimed to determine whether treatment should be stratified according to 18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) maximum standardized uptake values (SUVmax) in pan...

    Kyohei Ariake, Fuyuhiko Motoi, Hideo Shimomura in Journal of Gastrointestinal Surgery (2018)

  11. Article

    Open Access

    A long-term survival case treated with conversion surgery following chemotherapy after diagnostic metastasectomy for pancreatic cancer with synchronous liver metastasis

    Pancreatic cancer with distant metastases is classified as “unresectable,” for which the standard treatment is systemic chemotherapy. The effectiveness of radical resection for pancreatic cancer with distant m...

    Mitsuhiro Shimura, Masamichi Mizuma, Hiroki Hayashi, Akiko Mori in Surgical Case Reports (2017)

  12. No Access

    Article

    Predictive risk factors for peritoneal recurrence after pancreatic cancer resection and strategies for its prevention

    To evaluate the risk factors for peritoneal recurrence (PR) of pancreatic adenocarcinoma and to discuss the appropriate management strategies.

    Kyohei Ariake, Fuyuhiko Motoi, Hideo Ohtsuka, Koji Fukase, Kunihiro Masuda in Surgery Today (2017)

  13. Article

    Open Access

    Pancreatic neuroendocrine tumor with complete replacement of the pancreas by serous cystic neoplasms in a patient with von Hippel-Lindau disease: a case report

    von Hippel-Lindau disease is a dominantly inherited multi-system syndrome with neoplastic hallmarks. Pancreatic lesions associated with von Hippel-Lindau include serous cystic neoplasms, simple cysts, and neur...

    Shimpei Maeda, Fuyuhiko Motoi, Shuhei Oana, Kyohei Ariake in Surgical Case Reports (2017)

  14. Article

    Open Access

    Locally advanced pancreatic cancer successfully treated by distal pancreatectomy with celiac axis resection (DP-CAR) after S-1 with radiation therapy followed by gemcitabine/nab-paclitaxel therapy: a case report

    The prognosis for pancreatic cancer remains dismal because many patients are diagnosed with unresectable cancer at the initial diagnosis. Recently, conversion surgery was reported as an effective treatment for...

    Kyohei Ariake, Fuyuhiko Motoi, Masamichi Mizuma, Keigo Murakami in Surgical Case Reports (2017)

  15. No Access

    Article

    Solid pseudopapillary neoplasms of the pancreas: an 18-year experience at a single Japanese Institution

    This study investigated the clinicopathological features and surgical management of solid pseudopapillary neoplasms at a single institution in Japan.

    Takanori Morikawa, Tohru Onogawa, Shimpei Maeda, Tatsuyuki Takadate in Surgery Today (2013)

  16. No Access

    Article

    Paclitaxel as second-line chemotherapy in patients with gemcitabine-refractory pancreatic cancer: a retrospective study

    We evaluated the efficacy and feasibility of paclitaxel in patients with gemcitabine-refractory pancreatic cancer. We also evaluated the correlation between tumor marker decline and response rate.

    Shimpei Maeda, Fuyuhiko Motoi, Tohru Onogawa in International Journal of Clinical Oncology (2011)