1 Result(s)

Article

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Survival rates for pediatric patients suffering from mixed lineage leukemia (MLL)-rearranged leukemia remain below 50% and more targeted, less toxic therapies are urgently needed. A screening method optimized to ...

Klaartje Somers, Victoria W. Wen, Shiloh M. C. Middlemiss, Brenna Osborne… in Oncogene (2019)