![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Chapter and Conference Paper
Analysis of the Impact that Traffic Noise Has on High-Rise Buildings Under Different Road Network
With the development of our country's economy, the density of high-rise residential buildings and roads is increasing, so it is necessary to study the vertical distribution characteristics of high-rise buildin...
-
Article
Open AccessCorrection: Combination chemotherapy of valproic acid (VPA) and gemcitabine regulates STAT3/Bmi1 pathway to differentially potentiate the motility of pancreatic cancer cells
-
Article
Open AccessHigh glucose-upregulated PD-L1 expression through RAS signaling-driven downregulation of PTRH1 leads to suppression of T cell cytotoxic function in tumor environment
Nearly 80% of patients with pancreatic cancer suffer from glucose intolerance or diabetes. Pancreatic cancer complicated by diabetes has a more immunosuppressive tumor microenvironment (TME) and is associated ...
-
Article
Open AccessA novel staging system and clinical predictive nomogram for more accurate staging and prognosis of malignant pancreatic intraductal papillary mucinous neoplasms: a population-based study
The current guidelines of the American Joint Committee on Cancer (AJCC) for the staging of exocrine pancreatic tumors seem inapplicable to malignant pancreatic intraductal papillary mucinous neoplasms (IPMN). ...
-
Article
Open AccessExtraordinary optical transmission through periodic Drude-like graphene sheets using FDTD algorithms and its unconditionally stable approximate Crank–Nicolson implementation
Based upon the approximate Crank–Nicolson (CN) finite-difference time-domain method implementation, the unconditionally stable algorithm is proposed to investigate the wave propagation and transmission through...
-
Article
Graphene oxide as a photocatalytic nuclease mimicking nanozyme for DNA cleavage
Develo** nanomaterial-based enzyme mimics for DNA cleavage is an interesting challenge and it has many potential applications. Single-layered graphene oxide (GO) is an excellent platform for DNA adsorption. ...
-
Article
Open AccessCombination chemotherapy of valproic acid (VPA) and gemcitabine regulates STAT3/Bmi1 pathway to differentially potentiate the motility of pancreatic cancer cells
Gemcitabine is the standard first-line chemotherapy regimen for pancreatic cancer. However, its therapeutic value is substantially limited in pancreatic cancer patients due to occurrence of resistance towards ...
-
Article
Open AccessHigh glucose promotes pancreatic cancer cells to escape from immune surveillance via AMPK-Bmi1-GATA2-MICA/B pathway
Modulation of cell surface expression of MHC class I chain-related protein A/B (MICA/B) has been proven to be one of the mechanisms by which tumor cells escape from NK cell-mediated killing. Abnormal metabolic...
-
Article
Open AccessPrognostic accuracy of the serum lactate level, the SOFA score and the qSOFA score for mortality among adults with Sepsis
Sepsis is a common critical condition caused by the body’s overwhelming response to certain infective agents. Many biomarkers, including the serum lactate level, have been used for sepsis diagnosis and guiding...
-
Article
Open AccessTumor location as an indicator of survival in T1 resectable pancreatic ductal adenocarcinoma: a propensity score-matched analysis
The latest 8th edition of the AJCC staging system emphasizes the importance of tumor size however, the clinical significance of the combination of tumor location with tumor size remains unknown.
-
Chapter and Conference Paper
Analysis of Back-Flashover Lightning- Withstanding Level of 500-kV-Double-Circuit Transmission Lines
This chapter analyzes the lightning performance of 500-kV-double-circuit transmission lines by the Alternative Transient Performance-Electromagnetic Transient Program (ATP-EMTP). With towers using the multi-wa...