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Article
Perioperative Outcomes and Learning Curve of Robot-Assisted McKeown Esophagectomy
This study aimed to evaluate the perioperative outcomes of patients undergoing robot-assisted McKeown esophagectomy (RAME) and the learning curves of surgeons performing RAME at a single center.
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Article
Open AccessInhibition of XPO1 with KPT-330 induces autophagy-dependent apoptosis in gallbladder cancer by activating the p53/mTOR pathway
Gallbladder cancer (GBC) is a highly aggressive malignant cancer in the biliary system with poor prognosis. XPO1 (chromosome region maintenance 1 or CRM1) mediates the nuclear export of several proteins, mainl...
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Article
Open AccessUBAP2L promotes gastric cancer metastasis by activating NF-κB through PI3K/AKT pathway
Ubiquitin-associated protein 2-like (UBAP2L) is highly expressed in various types of tumors and has been shown to participate in tumor growth and metastasis; however, its role in gastric cancer (GC) remains un...
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Article
Quantitative detection of ricin in beverages using trypsin/Glu-C tandem digestion coupled with ultra-high-pressure liquid chromatography-tandem mass spectrometry
The toxic protein of ricin has drawn wide attention in recent years as a potential bioterrorism agent due to its high toxicity and wide availability. For the verification of the potential anti-terrorism activi...
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Article
Characterization of CD103+ CD8+ tissue-resident T cells in esophageal squamous cell carcinoma: may be tumor reactive and resurrected by anti-PD-1 blockade
Though therapy that promotes anti-tumor response about CD8+ tumor-infiltrating lymphocytes (TILs) has shown great potential, clinical responses to CD8+ TILs immunotherapy vary considerably, largely because of dif...
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Article
Open AccessNeoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for locally advanced oesophageal squamous cell carcinoma: a single-Centre, open-label, randomized, controlled, clinical trial (HCHTOG1903)
Neoadjuvant therapy plus oesophagectomy has been accepted as the standard treatment for patients with potentially curable locally advanced oesophageal cancer. No completed randomized controlled trial (RCT) has...
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Chapter
Distal Pancreatectomy with Splenic Preservation
Distal pancreatectomy (exsection of the pancreatic body and tail) can be operated with or without splenic preservation. The significance of preserving the spleen has been shown for lesions confined to the panc...
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Article
A sensitive quantification approach for detection of HETE-CP adduct after benzyl chloroformate derivatization using ultra-high-pressure liquid chromatography tandem mass spectrometry
Sulfur mustard (HD) reacts with human serum albumin (HSA) at Cys34 and produces a long-term biomarker of HD exposure. Here, we present a novel, sensitive, and convenient method for quantification of HD exposure b...
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Article
Open AccessBroadband gradient impedance matching using an acoustic metamaterial for ultrasonic transducers
High-quality broadband ultrasound transducers yield superior imaging performance in biomedical ultrasonography. However, proper design to perfectly bridge the energy between the active piezoelectric material a...
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Article
Effect of solid paraffin on the integrity of welded interfaces and properties of ultra-high molecular weight polyethylene
Ultra-high molecular weight polyethylene (UHMWPE) contains fusion defects, arising during the processing of the reactor powder. These defects have been implicated previously in failures of UHMWPE load-bearing ...
