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  1. Article

    Open Access

    PJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma

    Chemoresistance is a main reason for treatment failure in patients with nasopharyngeal carcinoma, but the exact regulatory mechanism underlying chemoresistance in nasopharyngeal carcinoma remains to be elucida...

    Sheng-Yan Huang, Sha Gong, Yin Zhao, Ming-Liang Ye, Jun-Yan Li in Nature Communications (2024)

  2. Article

    Open Access

    Transcription factor ATMIN facilitates chemoresistance in nasopharyngeal carcinoma

    Despite that the docectaxel-cisplatin-5-fluorouracil (TPF) induction chemotherapy has greatly improved patients’ survival and became the first-line treatment for advanced nasopharyngeal carcinoma (NPC), not al...

    Xue-Liang Fang, Qing-Jie Li, Jia-Yi Lin, Cheng-Long Huang in Cell Death & Disease (2024)

  3. Article

    Open Access

    The E3 ligase NEURL3 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma by promoting vimentin degradation

    Metastasis has emerged as the major reason of treatment failure and mortality in patients with nasopharyngeal carcinoma (NPC). Growing evidence links abnormal DNA methylation to the initiation and progression ...

    Shi-Qing Zhou, ** Feng, Ming-Liang Ye in Journal of Experimental & Clinical Cancer … (2024)

  4. Article

    Open Access

    DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation

    Emerging evidence indicates that DNA methylation plays an important role in the initiation and progression of nasopharyngeal carcinoma (NPC). DNAJA4 is hypermethylated in NPC, while its role in regulating NPC ...

    Qun Zhang, ** Feng, Xun-Hua Zhu, Shi-Qing Zhou, Ming-Liang Ye in Cell Death & Disease (2023)

  5. No Access

    Article

    The tumor immune microenvironment of nasopharyngeal carcinoma after gemcitabine plus cisplatin treatment

    Gemcitabine plus cisplatin (GP) chemotherapy is the standard of care for nasopharyngeal carcinoma (NPC). However, the mechanisms underpinning its clinical activity are unclear. Here, using single-cell RNA sequ...

    Jiawei Lv, Yuan Wei, Jian-Hua Yin, Yu-Pei Chen, Guan-Qun Zhou, Chen Wei in Nature Medicine (2023)

  6. Article

    Open Access

    TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models

    Although radiotherapy can promote antitumour immunity, the mechanisms underlying this phenomenon remain unclear. Here, we demonstrate that the expression of the E3 ubiquitin ligase, tumour cell-intrinsic tripa...

    Jun-Yan Li, Yin Zhao, Sha Gong, Miao-Miao Wang, Xu Liu in Nature Communications (2023)

  7. Article

    Open Access

    Correction: AR-induced long non-coding RNA LINC01503 facilitates proliferation and metastasis via the SFPQ-FOSL1 axis in nasopharyngeal carcinoma

    Shi-Wei He, Cheng Xu, Ying-Qing Li, Ying-Qin Li, Yin Zhao, Pan-Pan Zhang in Oncogene (2021)

  8. Article

    Open Access

    AR-induced long non-coding RNA LINC01503 facilitates proliferation and metastasis via the SFPQ-FOSL1 axis in nasopharyngeal carcinoma

    Increasing evidence indicates that long non-coding RNAs (lncRNAs) play vital roles in the tumorigenesis and progression of cancers. However, the functions and regulatory mechanisms of lncRNAs in nasopharyngeal...

    Shi-Wei He, Cheng Xu, Ying-Qing Li, Ying-Qin Li, Yin Zhao, Pan-Pan Zhang in Oncogene (2020)

  9. No Access

    Article

    Alkaline pressure oxidative leaching of bismuth-rich and arsenic-rich lead anode slime

    A new alkaline pressure oxidative leaching process (with NaNO3 as the oxidant and NaOH as the alkaline reagent) is proposed herein to remove arsenic, antimony, and lead from bismuth-rich and arsenic-rich lead ano...

    Yun-long He, Rui-dong Xu, Shi-wei He in International Journal of Minerals, Metallu… (2019)

  10. No Access

    Article

    Effect of NaNO3 concentration on anodic electrochemical behavior on the Sb surface in NaOH solution

    The effect of NaNO3 concentration on the anodic electrochemical behavior of antimony in 4 M NaOH solution was investigated using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) analyses. ...

    Yun-long He, Rui-dong Xu, Shi-wei He in International Journal of Minerals, Metallu… (2018)

  11. No Access

    Chapter and Conference Paper

    Location Method of Underground Pipeline Monitoring Point Based on Cavity Detection

    Aiming at the situation of major underground pipeline collapse accident to happen occasionally, we analyzed the cause of underground cavity, establishing underground pipeline risk index system based on cavity,...

    Wei Zhu, ** Sun, Ying nan Ma, Rui Song in Information Computing and Applications (2012)