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  1. No Access

    Article

    Membrane Tension Modulates the Effects of Apical Cholesterol on the Renal Epithelial Sodium Channel

    We used patch-clamp techniques and A6 distal nephron cells as a model to determine how cholesterol regulates the renal epithelial sodium channel (ENaC). We found that luminal methyl-β-cyclodextrin (mβCD, a cho...

    Shi-Peng Wei, Xue-Qi Li, Chu-Fang Chou, You-You Liang… in Journal of Membrane Biology (2007)

  2. No Access

    Article

    Regulation of the epithelial sodium channel by phosphatidylinositides: experiments, implications, and speculations

    Recent studies suggest that the activity of epithelial sodium channels (ENaC) is increased by phosphatidylinositides, especially phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) and phosphatidylinositol 3,4,5-tr...

    He-** Ma, Chu-Fang Chou, Shi-Peng Wei… in Pflügers Archiv - European Journal of Phys… (2007)