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  1. Article

    Open Access

    Combined impact of sleep and obesity on female infertility in the NHANES 2017–2020

    Sleep health and obesity may affect the risk of female infertility. However, few studies focused on the interaction of obesity and sleep health on the female infertility risk. This study aimed to evaluate the ...

    Zhe Wang, Yun-Hui Lai, Song-Yu Huang, Yu-Dong Liu, Shi-Ling Chen in BMC Women's Health (2024)

  2. Article

    Open Access

    Advanced oxidation protein products attenuate the autophagy-lysosome pathway in ovarian granulosa cells by modulating the ROS-dependent mTOR-TFEB pathway

    Oxidative stress dysfunction has recently been found to be involved in the pathogenesis of premature ovarian insufficiency (POI). Previously, we found that advanced oxidation protein products (AOPPs) in plasma...

    **ng-Yu Zhou, Yun-Hui Lai, Jun Zhang, Ying Li, **ao-Min Wu in Cell Death & Disease (2024)

  3. Article

    Open Access

    Elevated cell-free mitochondria DNA level of patients with premature ovarian insufficiency

    Premature ovarian insufficiency (POI) patients present with a chronic inflammatory state. Cell-free mitochondria DNA (cf-mtDNA) has been explored as a reliable biomarker for estimating the inflammation-related...

    **ng-Yu Zhou, Yi-Zhen Yang, Jun Zhang, **ao-Fei Zhang in BMC Pregnancy and Childbirth (2023)

  4. Article

    Open Access

    Plasma metabolomic characterization of premature ovarian insufficiency

    Premature ovarian insufficiency (POI) patients are predisposed to metabolic disturbances, including in lipid metabolism and glucose metabolism, and metabolic disorders appear to be a prerequisite of the typica...

    **ng-Yu Zhou, **n Li, Jun Zhang, Ying Li, **ao-Min Wu in Journal of Ovarian Research (2023)

  5. Article

    Open Access

    Intramuscular injection of human chorionic gonadotropin prior to secretory transformation in patients undergoing frozen-thawed embryo transfer cycles

    The major difference between a natural cycle and an artificially prepared cycle is the lack of luteinizing hormone (LH) peak in the latter. The LH/hCG receptors were identified to express in human endometrium ...

    Ling Deng, **n Chen, Christophe Blockeel in Reproductive Biology and Endocrinology (2020)

  6. No Access

    Article

    A Second Dose of GnRHa in Combination with Luteal GnRH Antagonist May Eliminate Ovarian Hyperstimulation Syndrome in Women with ≥30 Follicles Measuring ≥11 mm in Diameter on Trigger Day and/or Pre-trigger Peak Estradiol Exceeding 10 000 pg/mL

    This observational study included 21 patients at remarkably high risk of ovarian hyperstimulation syndrome (OHSS), characterized by more than 30 follicles measuring ≥11 mm in diameter on trigger day and/or pre...

    Ling Deng, Xue-lan Li, De-sheng Ye, Christophe Blockeel in Current Medical Science (2019)

  7. No Access

    Article

    Expression of TET and 5-HmC in Trophoblast Villi of Women with Normal Pregnancy and with Early Pregnancy Loss

    Increasing evidence suggests that epigenetic dysfunction may influence the stability of normal pregnancy. The ten-eleven translocation (TET) family and 5-hydroxymethylcytosine (5-hmC) were found to be linked w...

    Ai-hua Wu, Dong-yu Yang, Yu-dong Liu, **n Chen, Xu-long Chen in Current Medical Science (2018)

  8. No Access

    Article

    Follicular fluid Aβ40 concentrations may be associated with ongoing pregnancy following in vitro fertilization

    To determine whether Aβ40 levels in the follicular fluid (FF) of infertile women undergoing IVF demonstrate a relationship with IVF cycle parameters and outcome.

    Fu-Hua Duan, Shi-Ling Chen, **n Chen in Journal of Assisted Reproduction and Genet… (2014)

  9. Article

    Open Access

    Combined analysis of endometrial thickness and pattern in predicting outcome of in vitro fertilization and embryo transfer: a retrospective cohort study

    To evaluate the combined effect of endometrial thickness and pattern on clinical outcome in patients undergoing in vitro fertilization/intracytoplasmic sperm injection and embryo transfer (IVF/ICSI-ET).

    Shi-Ling Chen, Fang-Rong Wu, Chen Luo, **n Chen in Reproductive Biology and Endocrinology (2010)