6 Result(s)

Article

Epidemiological study of HER-2 mutations among EGFR wild-type lung adenocarcinoma patients in China

Human epidermal growth factor receptor (HER)-2 is a driver gene in non-small cell lung cancer (NSCLC). The present study evaluated the mutation rate of HER-2 within the wild-type epidermal growth factor receptor ...

Xuefei Li, Chao Zhao, Chunxia Su, Shengxiang Ren, **aoxia Chen, Caicun Zhou in BMC Cancer (2016)

Article

Comprehensive evaluation of NT5E/CD73 expression and its prognostic significance in distinct types of cancers

CD73 is one of the critical component in the formation of immunosuppressive microenvironment in cancers. We aimed to provide an overview of the current status of CD73 expression and its relationship with clini...

Tao Jiang, **aofeng Xu, Meng Qiao, Xuefei Li, Chao Zhao, Fei Zhou… in BMC Cancer (2018)

Article

Outcomes of Pemetrexed-based chemotherapies in HER2-mutant lung cancers

HER2 mutation has been found to be an oncogenic driver gene in non-small cell lung cancers(NSCLC) and HER2-directed therapies have shown promising results in this unique population, while little is known about it...

Yan Wang, Shijia Zhang, Fengying Wu, **g Zhao, Xuefei Li, Chao Zhao… in BMC Cancer (2018)

Article

Multi-cancer blood testing combined with PET-CT: road for hope to screen for cancer and guide intervention

Tao Jiang, Shengxiang Ren, Caicun Zhou in Signal Transduction and Targeted Therapy (2020)

Article

Characterization of evolution trajectory and immune profiling of brain metastasis in lung adenocarcinoma

Characterizing the evolutionary trajectory and immune profiling of brain metastasis (BM) may provide insights in the development of novel therapeutic strategies. Here, we performed whole-exome sequencing and m...

Tao Jiang, Yan Yan, Kun Zhou, Chunxia Su, Shengxiang Ren, Nan Li… in npj Precision Oncology (2021)

Article

Toripalimab plus chemotherapy as second-line treatment in previously EGFR-TKI treated patients with EGFR-mutant-advanced NSCLC: a multicenter phase-II trial

This multicenter phase-II trial aimed to investigate the efficacy, safety, and predictive biomarkers of toripalimab plus chemotherapy as second-line treatment in patients with EGFR-mutant-advanced NSCLC. Patients...

Tao Jiang, **yang Wang, Jie Zhang… in Signal Transduction and Targeted Therapy (2021)